ArticleProceedings of the National Academy of Sciences of the United States of America2019
Bone-inspired microarchitectures achieve enhanced fatigue life.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed.
- Digital composites with reprogrammable phase architectures.Science advances · 2026Article
- Self-supervised AI for decoding and designing disordered metamaterials.Science advances · 2026Article
- CT-based age-related trabecular redistribution in the proximal femur and its association with fracture patterns in elderly individuals with and without diabetes.Frontiers in endocrinology · 2026Article
- Pathophysiology of Bone Fragility in Type 2 Diabetes Mellitus.Current osteoporosis reports · 2025Review
- Accelerated Method for Determining the Fatigue Limit of Trabecular Bone.Materials (Basel, Switzerland) · 2025Article
- Fatigue Performance of 3D-Printed Poly-Lactic-Acid Bone Scaffolds with Triply Periodic Minimal Surface and Voronoi Pore Structures.Polymers · 2024Article
- Review
- Review
- Improved Ballistic Impact Resistance of Nanofibrillar Cellulose Films with Discontinuous Fibrous Bouligand Architecture.Journal of applied mechanics · 2024Article
- Three-Dimensional Printed Hydroxyapatite Bone Substitutes Designed by a Novel Periodic Minimal Surface Algorithm Are Highly Osteoconductive.3D printing and additive manufacturing · 2023Article
- Improving the Mechanical Properties of a Lattice Structure Composed of Struts with a Tri-Directional Elliptical Cylindrical Section via Selective Laser Melting.Materials (Basel, Switzerland) · 2023Article
- 3D-Printed Architected Materials Inspired by Cubic Bravais Lattices.ACS biomaterials science & engineering · 2023Article
- Distributions of Microdamage Are Altered Between Trabecular Rods and Plates in Cancellous Bone From Men With Type 2 Diabetes Mellitus.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2022Article
- Identifying Structure-Property Relationships of Micro-Architectured Porous Scaffolds through 3D Printing and Finite Element Analysis.Computational materials science · 2022Article
- Fragmentation of Beaded Fibres in a Composite.Materials (Basel, Switzerland) · 2022Article
- Carfilzomib inhibits the proliferation and apoptosis of multiple myeloma cells by inhibiting STAT1/COX-2/iNOS signaling pathway.Translational cancer research · 2022Article
- Frugal manufacturing in smart factories for widespread sustainable development.Royal Society open science · 2021Article
- Bringing Mechanical Context to Image-Based Measurements of Bone Integrity.Current osteoporosis reports · 2021Review
- Nature-inspired materials and structures using 3D Printing.Materials science & engineering. R, Reports : a review journal · 2021Article
- Characterization of Ultralow Density Cellular Solids: Lessons from 30 years of Bone Biomechanics Research.Advanced engineering materials · 2021Article
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Abstract
Microarchitectured materials achieve superior mechanical properties through geometry rather than composition. Although ultralightweight microarchitectured materials can have high stiffness and strength, application to durable devices will require sufficient service life under cyclic loading. Naturally occurring materials provide useful models for high-performance materials. Here, we show that in cancellous bone, a naturally occurring lightweight microarchitectured material, resistance to fatigue failure is sensitive to a microarchitectural trait that has negligible effects on stiffness and strength-the proportion of material oriented transverse to applied loads. Using models generated with additive manufacturing, we show that small increases in the thickness of elements oriented transverse to loading can increase fatigue life by 10 to 100 times, far exceeding what is expected from the associated change in density. Transversely oriented struts enhance resistance to fatigue by acting as sacrificial elements. We show that this mechanism is also present in synthetic microlattice structures, where fatigue life can be altered by 5 to 9 times with only negligible changes in density and stiffness. The effects of microstructure on fatigue life in cancellous bone and lattice structures are described empirically by normalizing stress in traditional stress vs. life (S-N) curves by √
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