Evidence map›Paper›PMID 31740614›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

Trisha J Grevengoed, Samuel A J Trammell, Michele K McKinney, Natalia Petersen, Rebecca L Cardone, Jens S Svenningsen, Daisuke Ogasawara, Christina C Nexøe-Larsen, Filip K Knop, Thue W Schwartz and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 51 citations in OpenAlex.

  1. Article
  2. AAV-mediated FGF21 gene therapy promotes health span extension by whole-body tissue-specific adaptations.Molecular therapy : the journal of the American Society of Gene Therapy · 2026
    Article
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  16. A PTER-dependent pathway of taurine metabolism linked to energy balance.bioRxiv : the preprint server for biology · 2024
    Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Trisha J GrevengoedNovo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.ORCID 0000-0003-4433-3950
Samuel A J TrammellNovo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.
Michele K McKinneyDepartment of Cell Biology, The Scripps Research Institute, La Jolla, CA 92037.
Natalia PetersenNovo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.
Rebecca L CardoneDepartment of Internal Medicine, Yale School of Medicine, New Haven, CT 06519.
Jens S SvenningsenNovo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.
Daisuke OgasawaraDepartment of Cell Biology, The Scripps Research Institute, La Jolla, CA 92037.
Christina C Nexøe-LarsenCenter for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, 2900 Hellerup, Denmark.
Filip K KnopNovo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.
Thue W SchwartzNovo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.ORCID 0000-0002-0261-6904
Richard G KibbeyDepartment of Internal Medicine, Yale School of Medicine, New Haven, CT 06519.
Benjamin F CravattDepartment of Cell Biology, The Scripps Research Institute, La Jolla, CA 92037; cravatt@scripps.edu gillum@sund.ku.dk.
Matthew P GillumNovo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark; cravatt@scripps.edu gillum@sund.ku.dk.ORCID 0000-0003-4893-012X
University of Copenhagen · DKScripps Research Institute · USYale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Yale Diabetes Research CenterP30DK045735 · NIDDK · YALE UNIVERSITY · PI Kevan C Herold, GERALD I SHULMAN · 1993 to 2026
$44.0M
CHEMOPROTEOMIC METHODS FOR SERINE HYDROLASE INHIBITOR DEVELOPMENTR01DA033760 · NIDA · SCRIPPS RESEARCH INSTITUTE, THE · PI CRAVATT, BENJAMIN F, SCAMPAVIA, LOUIS DANIEL · 2012 to 2021
$5.1M
Chastening the double-edged sword of glucose metabolism in beta-cellsR01DK110181 · NIDDK · YALE UNIVERSITY · PI KIBBEY, RICHARD G · 2016 to 2019
$1.7M
NCATS NIH HHS UL1 TR001863NIDA NIH HHS R01 DA033760NIDDK NIH HHS P30 DK045735NIDDK NIH HHS R01 DK110181
6 · The paper itself

Abstract

Fatty acid amide hydrolase (FAAH) degrades 2 major classes of bioactive fatty acid amides, the

Indexed as

AmidohydrolasesAmino Acid SubstitutionAnimalsBlood GlucoseDisease Models, AnimalEatingEthanolaminesFatty Acid Amide HydrolasesFemaleGlucagonGlucagon-Like Peptide 1Glucose Tolerance TestHumansInjections, IntravenousInsulinIslets of LangerhansAmidohydrolasesBlood GlucoseEthanolaminesFatty Acid Amide HydrolasesGlucagonGlucagon-Like Peptide 1GPR119 protein, humanGpr119 protein, mouseInsulinN-acylethanolaminesN-oleoyl taurineOleic AcidsReceptors, G-Protein-CoupledTaurinefatty acid amide hydrolaselipid signalingmetabolismN-acyl taurines

Identifiers

PMID31740614
PMCPMC6900532
OpenAlexW2991143099

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.