ArticleThe Journal of biological chemistry2019
Wnt family member 4 (WNT4) and WNT3A activate cell-autonomous Wnt signaling independent of porcupine
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Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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0cells of the map it votes in
23citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
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Who cites it
23 citing papers in PubMed, 38 citations in OpenAlex.
- Altered MDC1 Interactions and Dysfunctional DNA Repair in Lobular Breast Cancer Confers Sensitivity to PARP Inhibition.Cancer research · 2026Article
- Reciprocal inhibition of Wnt signaling pathways pattern the interconnection of epithelial tubules in the regenerating zebrafish kidney.Development (Cambridge, England) · 2026Article
- SM08502-Mediated β-Catenin Repression Synergizes with Olaparib to Inhibit Tumor Progression.Cancer research communications · 2025Article
- NKD2 as a Mediator of IFIX Antioncogene-Induced Wnt Signalling and Epithelial-Mesenchymal Transition in Human OSCC.Journal of cellular and molecular medicine · 2025Article
- Basal-epithelial subpopulations underlie and predict chemotherapy resistance in triple-negative breast cancer.EMBO molecular medicine · 2024Article
- WNT4 Regulates Cellular Metabolism via Intracellular Activity at the Mitochondria in Breast and Gynecologic Cancers.Cancer research communications · 2024Article
- A WNT4- and DKK3-driven canonical to noncanonical Wnt signaling switch controls multiciliogenesis.Journal of cell science · 2023Article
- A stromal lineage maintains crypt structure and villus homeostasis in the intestinal stem cell niche.BMC biology · 2023Article
- Article
- The role of Evi/Wntless in exporting Wnt proteins.Development (Cambridge, England) · 2023Review
- Roles and action mechanisms of WNT4 in cell differentiation and human diseases: a review.Cell death discovery · 2021Review
- Mediator of DNA Damage Checkpoint 1 (MDC1) Is a Novel Estrogen Receptor Coregulator in Invasive Lobular Carcinoma of the Breast.Molecular cancer research : MCR · 2021Article
- WNT4 Balances Development vs Disease in Gynecologic Tissues and Women's Health.Endocrinology · 2021Review
- Palmitoleate Protects against Zika Virus-Induced Placental Trophoblast Apoptosis.Biomedicines · 2021Article
- A Dominant Heterozygous Mutation inFrontiers in cell and developmental biology · 2021Article
- Selective Surface and Intraluminal Localization of Wnt Ligands on Small Extracellular Vesicles Released by HT-22 Hippocampal Neurons.Frontiers in cell and developmental biology · 2021Article
- Estrogen Regulation of mTOR Signaling and Mitochondrial Function in Invasive Lobular Carcinoma Cell Lines Requires WNT4.Cancers · 2020Article
- Wnt Signaling in Gynecologic Malignancies.International journal of molecular sciences · 2020Review
- Review
- Aberrant WNT/CTNNB1 Signaling as a Therapeutic Target in Human Breast Cancer: Weighing the Evidence.Frontiers in cell and developmental biology · 2020Review
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Deviyani M RaoDepartment of Pathology, University of Colorado Anschutz Medical Campus, Aurora, Colorado 80045.ORCID 0000-0002-6923-4492
Madeleine T ShacklefordDepartment of Pathology, University of Colorado Anschutz Medical Campus, Aurora, Colorado 80045.ORCID 0000-0003-2599-1747
Evelyn K BordeauxDepartment of Pathology, University of Colorado Anschutz Medical Campus, Aurora, Colorado 80045.ORCID 0000-0001-9264-0205
Joseph L SottnikDepartment of Pathology, University of Colorado Anschutz Medical Campus, Aurora, Colorado 80045.ORCID 0000-0002-0263-3608
Rebecca L FergusonDepartment of Pathology, University of Colorado Anschutz Medical Campus, Aurora, Colorado 80045.
Tomomi M YamamotoDepartment of Obstetrics and Gynecology, University of Colorado Anschutz Medical Campus, Aurora, Colorado 80045.
Elizabeth A WellbergDepartment of Pathology, University of Colorado Anschutz Medical Campus, Aurora, Colorado 80045.
Benjamin G BitlerDepartment of Obstetrics and Gynecology, University of Colorado Anschutz Medical Campus, Aurora, Colorado 80045.ORCID 0000-0002-5809-5271
Matthew J SikoraDepartment of Pathology, University of Colorado Anschutz Medical Campus, Aurora, Colorado 80045 matthew.sikora@cuanschutz.edu.ORCID 0000-0003-2915-7442
University of Colorado Anschutz Medical Campus · US
Funding
PREDOCTORAL TRAINING PROGRAM IN PHARMACOLOGYT32GM007635 · NIGMS · UNIVERSITY OF COLORADO DENVER · PI DELL'ACQUA, MARK L · 1985 to 2023
$6.1MTargeting Wnt signaling to overcome PARP inhibitor resistance in ovarian cancerR00CA194318 · NCI · UNIVERSITY OF COLORADO DENVER · PI BITLER, BENJAMIN G · 2017 to 2019
$745kWNT4 IN ENDOCRINE RESPONSE AND RESISTANCE IN INVASIVE LOBULAR CARCINOMAR00CA193734 · NCI · UNIVERSITY OF COLORADO DENVER · PI SIKORA, MATTHEW J · 2017 to 2019
$703kElucidating the function of WNT4 in endocrine response and resistance in invasive lobular carcinomaK99CA193734 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SIKORA, MATTHEW J · 2015 to 2016
$256kNCI NIH HHS K99 CA193734NCI NIH HHS R00 CA193734NCI NIH HHS R00 CA194318NIGMS NIH HHS T32 GM007635
Abstract
Porcupine
Indexed as
Wnt Signaling PathwayAcyltransferasesCell Line, TumorCell ProliferationCoculture TechniquesCulture Media, ConditionedFulvestrantHumansIntracellular Signaling Peptides and ProteinsMembrane ProteinsParacrine CommunicationProtein TransportReceptors, G-Protein-CoupledRNA InterferenceRNA, Small InterferingWnt3A ProteinAcyltransferasesCulture Media, ConditionedFulvestrantIntracellular Signaling Peptides and ProteinsMembrane ProteinsPORCN protein, humanReceptors, G-Protein-CoupledRNA, Small InterferingWLS protein, humanWnt3A ProteinWnt4 Proteinbreast cancercancer biologycell growthcell signalingglycoprotein secretionovarian cancerPORCNprotein secretionWNT3AWNT4Wnt pathwayWnt signaling
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.