Evidence map›Paper›PMID 31740578›Full record

ArticleGenome research2019

Chromatin-sensitive cryptic promoters putatively drive expression of alternative protein isoforms in yeast.

Wu Wei, Bianca P Hennig, Jingwen Wang, Yujie Zhang, Ilaria Piazza, Yerma Pareja Sanchez, Christophe D Chabbert, Sophie H Adjalley, Lars M Steinmetz, Vicent Pelechano

Open access · bronzeAbstract read
In one paragraph

Article in Genome research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
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  3. A data-driven genome annotation approach for cassava.The Plant journal : for cell and molecular biology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 6 countries.

Wu Wei *Center for Biomedical Informatics, Shanghai Engineering Research Center for Big Data in Pediatric Precision Medicine, Shanghai Children's Hospital, Shanghai Jiao Tong University, Shanghai 200040, China.ORCID 0000-0001-5643-8739
Bianca P HennigEuropean Molecular Biology Laboratory (EMBL), Genome Biology Unit, 69117 Heidelberg, Germany.ORCID 0000-0002-7733-8160
Jingwen WangSciLifeLab, Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, 171 65 Solna, Sweden.ORCID 0000-0001-9688-8793
Yujie ZhangSciLifeLab, Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, 171 65 Solna, Sweden.ORCID 0000-0002-4926-028X
Ilaria PiazzaInstitute of Molecular Systems Biology, Department of Biology, ETH Zürich, 8093 Zürich, Switzerland.ORCID 0000-0001-5895-6134
Yerma Pareja SanchezSciLifeLab, Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, 171 65 Solna, Sweden.ORCID 0000-0003-2008-5390
Christophe D ChabbertEuropean Molecular Biology Laboratory (EMBL), Genome Biology Unit, 69117 Heidelberg, Germany.ORCID 0000-0001-7851-4640
Sophie H AdjalleyWellcome Sanger Institute, Hinxton, CB10 1SA, United Kingdom.ORCID 0000-0002-5666-7088
Lars M SteinmetzStanford Genome Technology Center, Stanford University, Palo Alto, California 94304, USA.ORCID 0000-0002-3962-2865
Vicent Pelechano *SciLifeLab, Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, 171 65 Solna, Sweden.ORCID 0000-0002-9415-788X
Science for Life Laboratory · SEEuropean Molecular Biology Laboratory · DEETH Zurich · CHShanghai Jiao Tong University · CNWellcome Sanger Institute · GB

Funding

WHOLE YEAST GENOME TRANSCRIPTIONAL AND FUNCTIONAL GENE MAPS--A FEASIBILITY STUDYP01HG000205 · NHGRI · STANFORD UNIVERSITY · PI DAVIS, RONALD WAYNE, HOWE, ROGER THOMAS · 1990 to 2016
$120.9M
NHGRI NIH HHS P01 HG000205
6 · The paper itself

Abstract

Cryptic transcription is widespread and generates a heterogeneous group of RNA molecules of unknown function. To improve our understanding of cryptic transcription, we investigated their transcription start site (TSS) usage, chromatin organization, and posttranscriptional consequences in

Indexed as

ChromatinGene Expression Regulation, FungalPromoter Regions, GeneticSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsTranscription Initiation SiteHumansProtein IsoformsRNA, FungalRNA StabilityChromatinProtein IsoformsRNA, FungalSaccharomyces cerevisiae Proteins

Identifiers

PMID31740578
PMCPMC6886497
OpenAlexW2986506716

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.