Evidence map›Paper›PMID 31740555›Full record

ArticleAntimicrobial agents and chemotherapy2020

Precision Medicine and Mysteries in Clinical Microbiology: Rationalizing Epidemiology, Genotype, and Phenotype To Guide Therapeutics.

Federico Perez, Robert A Bonomo

Open access · greenAbstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Characterization of Metallo β-Lactamase ProducingAntibiotics (Basel, Switzerland) · 2024
    Article
  2. Review
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Federico PerezMedical and Research Services and Geriatrics Research, Education and Clinical Center (GRECC), VA Northeast Ohio Healthcare System and Louis Stokes Cleveland VA Medical Center, Cleveland, Ohio, USA federico.perez@va.gov robert.bonomo@va.gov.
Robert A BonomoMedical and Research Services and Geriatrics Research, Education and Clinical Center (GRECC), VA Northeast Ohio Healthcare System and Louis Stokes Cleveland VA Medical Center, Cleveland, Ohio, USA federico.perez@va.gov robert.bonomo@va.gov.
Louis Stokes Cleveland VA Medical Center · USUniversity Hospitals of Cleveland · US

Funding

Understanding B-Lactam Resistance in Acinetobacter baumanniiR01AI072219 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI ROBERT A. BONOMO, Philip N. Rather · 2007 to 2026
$6.6M
Understanding ceftazidime resistance in SHV B-LactamasesR01AI063517 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI BONOMO, ROBERT A. · 2005 to 2023
$4.9M
A Mechanism-Based Approach to Metallo-beta-Lactamase InhibitionR01AI100560 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI BONOMO, ROBERT A., SPENCER, JAMES · 2012 to 2022
$4.4M
The Continuing Challenge of Carbapenemases in K. pneumoniae: KPC-2 & NDM-1I01BX001974 · VA · LOUIS STOKES CLEVELAND VA MEDICAL CENTER · PI BONOMO, ROBERT A. · 2013 to 2024
–
BLRD VA I01 BX001974NIAID NIH HHS R01 AI063517NIAID NIH HHS R01 AI072219NIAID NIH HHS R01 AI100560
6 · The paper itself

Abstract

Whole-genome sequencing (WGS) using MinION was used to characterize high-risk clones of

Indexed as

beta-LactamasesPrecision MedicineGenotypeHumansIndiaKlebsiella pneumoniaeMicrobial Sensitivity TestsPhenotypebeta-Lactamases

Identifiers

PMID31740555
PMCPMC6985733
OpenAlexW2983639136

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.