ArticleCMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne2019
Age-standardized cancer-incidence trends in Canada, 1971-2015.
Article in CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 43 citations in OpenAlex.
- The circadian architecture of tumor immunity: mechanistic insights and treatment strategies.Biomarker research · 2026Review
- Optimizing Care Pathways from Screening/Detection to Survivorship for Early Age Onset Cancer Patients in Canada.Current oncology (Toronto, Ont.) · 2026Article
- Relationship between myeloid skewing and colorectal cancer risk in the Framingham Heart Study.Frontiers in oncology · 2026Article
- Article
- Population-based differences in cancer incidence between immigrants and non-immigrants in Canada between 1992 and 2015.BMC public health · 2025Article
- Development and Validation of a Competitive Risk Model in Elderly Patients with Transitional Cell Bladder Carcinoma.Medical science monitor : international medical journal of experimental and clinical research · 2025Article
- Divergent trajectories in pancreatic cancer burden among older adults (55+): a GBD 2021 analysis revealing China's dual epidemic of aging and population growth (1990-2045).Frontiers in public health · 2025Article
- Uterine cancer incidence trends and 5-year relative survival by race/ethnicity and histology among women under 50 years.American journal of obstetrics and gynecology · 2024Article
- Strategies to accelerate the elimination of cervical cancer in British Columbia, Canada: a modelling study.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2024Article
- The risk of skin cancer in women who carry BRCA1 or BRCA2 mutations.Hereditary cancer in clinical practice · 2024Article
- Article
- THE GROWING EVIDENCE OF THE RELATIONSHIP BETWEEN OBESITY AND CANCER AND THE ROLE OF BARIATRIC SURGERY.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2024Review
- Age-Specific Trends of Invasive Cervical Cancer Incidence in British Columbia, Canada, 1971-2017.Current oncology (Toronto, Ont.) · 2023Article
- Impact of the COVID-19 pandemic on cancer diagnoses, stage and survival in Alberta.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2023Article
- The clinico-pathological characteristics of surgically treated young women with NSCLC.Translational lung cancer research · 2022Article
- Incidence, prognostic factors and survival in bladder cancer patients: a population-based study.Translational cancer research · 2022Article
- Incidence trends for twelve cancers in younger adults-a rapid review.British journal of cancer · 2022Review
- The Path to Eliminating Cervical Cancer in Canada: Past, Present and Future Directions.Current oncology (Toronto, Ont.) · 2022Review
- The Incidence of Cancer Is Increased in Hospitalized Adult Patients With Obstructive Sleep Apnea in China: A Retrospective Cohort Study.Frontiers in oncology · 2022Article
- Incidence and mortality rates of keratinocyte carcinoma from 1998-2017: a population-based study of sex differences in Ontario, Canada.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2021Article
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlthough cancer incidence over time is well documented in Canada, trends by birth cohort and age group are less well known. We analyzed age- and sex-standardized incidence trends in Canada for 16 major cancer sites and all cancers combined.
methodsWe obtained nationally representative population-based cancer incidence data in Canada between 1971 and 2015 from the National Cancer Incidence Reporting System (1969-1992) and the Canadian Cancer Registry (1992-2015). We analyzed cancer-incidence trends, reported as annual percent change (APC) for each 10-year group from age 20 to 89 years. We also estimated age-adjusted incidence rate ratios from fitted birth cohort models.
resultsAcross most age categories, the most recent trends show significant decreases in the incidence of cervical (APC -8.8% to -0.33%), lung (men: -7.42% to -0.36%; women: -6.27% to 1.07%), bladder (women: -4.12% to -0.07%; men: -5.13% to -0.38%) and prostate cancer (-11.11% to -1.11%). Significant increasing trends were observed for kidney, thyroid and uterine cancers. Overall incidence has increased among both sexes younger than 50 years of age, with recent increases in pancreatic cancer among men, breast cancer among women and colorectal cancer among both sexes. From the birth cohort analysis, we observed increasing trends in colorectal, liver and prostate cancers among men; kidney cancer and melanoma among women; and thyroid cancer among both sexes. We observed decreasing trends in cervical and ovarian cancers, and in bladder and lung cancers among men.
interpretationCancer incidence is decreasing at many sites targeted by primary-prevention efforts, such as smoking cessation and screening programs. Substantial increases in incidence among younger populations are driven by cancers possibly associated with obesity.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.