Evidence map›Paper›PMID 31740505›Full record

ArticlePlant physiology2020

Compensatory Mutations in GI and ZTL May Modulate Temperature Compensation in the Circadian Clock.

Tae-Sung Kim, Lei Wang, Yeon Jeong Kim, David E Somers

Abstract read
In one paragraph

Article in Plant physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. The NaProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  9. Evolutionary Analysis and Functional Identification of Clock-AssociatedInternational journal of molecular sciences · 2022
    Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Plant signaling & behavior · 2021
    Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tae-Sung KimDepartment of Molecular Genetics, The Ohio State University, Columbus, Ohio 43210.ORCID 0000-0001-7837-6479
Lei WangDepartment of Molecular Genetics, The Ohio State University, Columbus, Ohio 43210.ORCID 0000-0002-4912-5387
Yeon Jeong KimDepartment of Molecular Genetics, The Ohio State University, Columbus, Ohio 43210.ORCID 0000-0003-2292-1372
David E SomersDepartment of Molecular Genetics, The Ohio State University, Columbus, Ohio 43210 somers.24@osu.edu.ORCID 0000-0001-5170-2430

Funding

Post-translational control mechanisms of the circadian clockR01GM093285 · NIGMS · OHIO STATE UNIVERSITY · PI SOMERS, DAVID E · 2010 to 2018
$2.7M
NIGMS NIH HHS R01 GM093285
6 · The paper itself

Abstract

Circadian systems share the three properties of entrainment, free-running period, and temperature compensation (TC). TC ensures nearly the same period over a broad range of physiologically relevant temperatures; however, the mechanisms behind TC remain poorly understood. Here, we identify single point mutations in two key elements of the Arabidopsis circadian clock, GIGANTEA (GI) and ZEITLUPE (ZTL), which likely act as compensatory substitutions to establish a remarkably constant free-running period over a wide range of temperatures. Using near-isogenic lines generated from the introgression of the Cape Verde Islands (Cvi) alleles of GI and ZTL into the Landsberg

Indexed as

AllelesAmino Acid MotifsArabidopsisArabidopsis ProteinsCabo VerdeCell NucleusCircadian ClocksCytosolDarknessGenotypePhenotypePlants, Genetically ModifiedPoint MutationPolymorphism, GeneticProtein BindingSeedlingsArabidopsis ProteinsGI protein, ArabidopsisZTL protein, Arabidopsis

Identifiers

PMID31740505
PMCPMC6997678

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.