Evidence map›Paper›PMID 31739858›Full record

ArticleJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2019

Chronic Opioid Therapy and Sleep: An American Academy of Sleep Medicine Position Statement.

Ilene M Rosen, R Nisha Aurora, Douglas B Kirsch, Kelly A Carden, Raman K Malhotra, Kannan Ramar, Fariha Abbasi-Feinberg, David A Kristo, Jennifer L Martin, Eric J Olson and 4 more

Abstract readConsensus Statement
In one paragraph

Article in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Prevalence of sleep-disordered breathing in opioid users with chronic pain: a systematic review and meta-analysis.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2020
    Pooled it
  2. Treatment for patients with sleep apnea on opioids for chronic pain: results of the OpSafe trial.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2021
    Trial
  3. Trial
  4. Review
  5. Article
  6. Article
  7. The interplay of circadian rhythms and cancer pain: a narrative review.Journal of anesthesia, analgesia and critical care · 2026
    Review
  8. Review
  9. Prescribing controlled substances in sleep medicine clinics: an overview of legal issues and best safety practices.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
    Review
  10. Review
  11. Review
  12. Treatment of sleep-disordered breathing in opioid users with adaptive servo-ventilation: a subgroup analysis of the European READ-ASV registry.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
    Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
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  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Ilene M RosenDivision of Sleep Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
R Nisha AuroraDepartment of Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey.
Douglas B KirschSleep Medicine, Atrium Health, Charlotte, North Carolina.
Kelly A CardenSaint Thomas Medical Partners - Sleep Specialists, Nashville, Tennessee.
Raman K MalhotraSleep Medicine Center, Washington University School of Medicine, St. Louis, Missouri.
Kannan RamarDivision of Pulmonary and Critical Care Medicine, Center for Sleep Medicine, Mayo Clinic, Rochester, Minnesota.
Fariha Abbasi-FeinbergMillennium Physician Group, Fort Myers, Florida.
David A KristoUniversity of Pittsburgh, Pittsburgh, Pennsylvania.
Jennifer L MartinVeteran Affairs Greater Los Angeles Healthcare System, North Hills, California.
Eric J OlsonDivision of Pulmonary and Critical Care Medicine, Center for Sleep Medicine, Mayo Clinic, Rochester, Minnesota.
Carol L RosenDepartment of Pediatrics, Case Western Reserve University, University Hospitals - Cleveland Medical Center, Cleveland, Ohio.
James A RowleyWayne State University, Detroit, Michigan.
Anita V ShelgikarUniversity of Michigan Sleep Disorders Center, University of Michigan, Ann Arbor, Michigan.
American Academy of Sleep Medicine Board of Directors

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

None: There is a complex relationship among opioids, sleep and daytime function. Patients and medical providers should be aware that chronic opioid therapy can alter sleep architecture and sleep quality as well as contribute to daytime sleepiness. It is also important for medical providers to be cognizant of other adverse effects of chronic opioid use including the impact on respiratory function during sleep. Opioids are associated with several types of sleep-disordered breathing, including sleep-related hypoventilation, central sleep apnea (CSA), and obstructive sleep apnea (OSA). Appropriate screening, diagnostic testing, and treatment of opioid-associated sleep-disordered breathing can improve patients' health and quality of life. Collaboration among medical providers is encouraged to provide high quality, patient-centered care for people who are treated with chronic opioid therapy.

Indexed as

Analgesics, OpioidHumansPractice Guidelines as TopicSleepSleep Apnea SyndromesSleep Medicine SpecialtyAnalgesics, Opioid

Identifiers

PMID31739858
PMCPMC6853382

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.