Evidence map›Paper›PMID 31739851›Full record

ArticleJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2019

Effect of Positive Airway Pressure Therapy on Drowsy Driving in a Large Clinic-Based Obstructive Sleep Apnea Cohort.

Harneet K Walia, Nicolas R Thompson, Maeve Pascoe, Maleeha Faisal, Douglas E Moul, Irene Katzan, Reena Mehra, Nancy Foldvary-Schaefer

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07434921 (TESTING AN MTM THEORY-BASED INTERVENTION ON REDUCING DROWSY DRIVING BEHAVIOR, "STAY AWAKE, STAY ALIVE, ©" AMONG COLLEGE STUDENTS), which is not on this map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07434921 naenrolling by invitationnot on this mapstarted 2026, after this paper: background citation

Testing an mtm theory-based intervention on reducing drowsy driving behavior, "stay awake, stay alive, ©" among college students: an educational randomized controlled trial

TypeinterventionalSponsorUniversity of Nevada, Las VegasRan2026 to 2026Enrolled72ConditionsDrowsiness, Sleep Deprivation, FatigueArmsMTM Theory based intervention, Standard AAA Knowledge based
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Harneet K WaliaSleep Disorders Center, Neurological Institute, Cleveland Clinic, Cleveland, Ohio.
Nicolas R ThompsonDepartment of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio.
Maeve PascoeSleep Disorders Center, Neurological Institute, Cleveland Clinic, Cleveland, Ohio.
Maleeha FaisalSleep Disorders Center, Neurological Institute, Cleveland Clinic, Cleveland, Ohio.
Douglas E MoulSleep Disorders Center, Neurological Institute, Cleveland Clinic, Cleveland, Ohio.
Irene KatzanCerebrovascular Center, Neurological Institute, Cleveland Clinic, Cleveland, Ohio.
Reena MehraSleep Disorders Center, Neurological Institute, Cleveland Clinic, Cleveland, Ohio.
Nancy Foldvary-SchaeferSleep Disorders Center, Neurological Institute, Cleveland Clinic, Cleveland, Ohio.
Cleveland Clinic · US

Funding

Pulmonary Vascular Disease Phenomics Program (PVDOMICS) Data Coordinating CenterU01HL125177 · NHLBI · CLEVELAND CLINIC LERNER COM-CWRU · PI BECK, GERALD J, ERZURUM, SERPIL C. · 2014 to 2020
$20.0M
Impact of Low Flow Nocturnal Oxygen Therapy On Hospital Readmission/Mortalityin Patients with Heart Failure and Central Sleep Apneal (LOFT-HF)UG3HL140144 · NHLBI · OHIO STATE UNIVERSITY · PI ABRAHAM, WILLIAM TOBER · 2018 to 2018
$742k
NHLBI NIH HHS U01 HL125177NHLBI NIH HHS UG3 HL140144
6 · The paper itself

Abstract

STUDY

objectivesDrowsy driving related to obstructive sleep apnea (OSA) represents an important public health problem with limited data on the effect of positive airway pressure (PAP) therapy. We hypothesize that PAP therapy will reduce self-reported drowsy driving in a large clinic-based OSA cohort.

methodsDrowsy driving (self-reported near-accidents/accidents) incidents from baseline to after PAP therapy (stratified by adherence) were compared in a cohort of 2,059 patients with OSA who initiated PAP therapy from January 1, 2010 to December 31, 2014. Multivariable logistic regression models evaluated the dependence of change in drowsy driving incidents on other factors, including change in Epworth Sleepiness Scale (ESS) and Patient Health Questionnaire-9 (PHQ9) scores.

resultsIn the entire cohort (age 56.0 ± 13.1 years, 45.4% female, 76.0% white, average follow-up 124.4 ± 67.3 days), drowsy driving incidents reduced from 14.2 to 6.9% after PAP therapy (P < .001). In subgroups, drowsy driving incidents reduced from 14% to 5.3% (P < .001) in patients who self-reported adherence to PAP therapy and 14.1% to 5.3% (P < .001) in patients objectively adherent to PAP therapy. For each one-point improvement in Epworth Sleepiness Scale score, the odds of drowsy driving decreased by about 14% (odds ratio 0.86, 95% confidence interval 0.82 to 0.90).

conclusionsIn this clinic-based cohort, drowsy driving improved after adherent PAP usage, with greater drowsy driving risk for those with greater sleep propensity. This highlights the importance of and need for routine drowsy driving assessments and careful clinical attention to PAP adherence and sleep propensity in this population. Our findings should be confirmed and may be used to provide support for initiatives to address the public health issue of drowsy driving.

Indexed as

Continuous Positive Airway PressureAccidents, TrafficAutomobile DrivingFemaleHumansMaleMiddle AgedSleep Apnea, Obstructivedrowsy drivingobstructive sleep apneapositive airway pressure

Identifiers

PMID31739851
PMCPMC6853402
OpenAlexW2988037301

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.