SynthesisBMC musculoskeletal disorders2019
Comparison between minimally invasive plate osteosynthesis and open reduction-internal fixation for proximal humeral fractures: a meta-analysis based on 1050 individuals.
Synthesis in BMC musculoskeletal disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.
- Interventions for treating proximal humeral fractures in adults.The Cochrane database of systematic reviews · 2022Pooled it
- Comparison of Surgical Outcomes and Perioperative Laboratory Parameters Following Minimally Invasive Plate Osteosynthesis versus Conventional Plating in Long Bone Fractures.Journal of orthopaedic case reports · 2026Article
- Does the operative technique (MIPO vs. ORIF) influence surgical outcomes and complications in proximal humerus fractures? A matched-pair analysis.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026Article
- ORIF of three- and four-part proximal humeral fractures: a retrospective study of long-term clinical and complication outcomes of two-plate fixation methods.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2026Article
- Combination of MIPO and WALANT procedure versus ORIF and general anesthesia in midshaft clavicle fracture: a prospective comparative cohort study.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2025Article
- Article
- The Clinical and Radiological Outcomes and Complications of Bilboquet Implant for Proximal Humerus Fractures: A Systematic Review.Journal of clinical medicine · 2024Review
- The Application of Bidirectional Rapid Reductor in Minimally Invasive Plate Osteosynthesis for the Treatment of Proximal Humeral Fractures: A Case Series.Orthopaedic surgery · 2024Article
- Proximal humerus fractures: deltopectoral open reduction and internal fixation vs deltosplit minimally invasive plate osteosynthesis: which surgical approach provides superior results?EFORT open reviews · 2023Article
- Proximal humerus fractures (PHFs): comparison of functional outcome 1 year after minimally invasive plate osteosynthesis (MIPO) versus open reduction internal fixation (ORIF).European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2022Article
- PHILOS Synthesis for Proximal Humerus Fractures Has High Complications and Reintervention Rates: A Systematic Review and Meta-Analysis.Life (Basel, Switzerland) · 2022Review
- A virtual reality simulator for training the surgical reduction of patient-specific supracondylar humerus fractures.International journal of computer assisted radiology and surgery · 2022Article
- The role of minimally invasive plate osteosynthesis (MIPO) technique for treating 3- and 4-part proximal humerus fractures in the elderly - a case study.Acta bio-medica : Atenei Parmensis · 2021Article
- Comparison between MIPO and the deltopectoral approach with allogenous fibular bone graft in proximal humeral fractures.Clinics in shoulder and elbow · 2020Article
- Comparison between minimally invasive deltoid-split and extended deltoid-split approach for proximal humeral fractures: a case-control study.BMC musculoskeletal disorders · 2020Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundThis meta-analysis aimed to compare the clinical outcomes and complications of minimally invasive plate osteosynthesis (MIPO) and open reduction-internal fixation (ORIF) in patients with proximal humeral fractures.
methodsWe searched PubMed, EMBASE, Ovid, and the Cochrane Library to identify all relevant studies from inception to April 2019. Cochrane Collaboration's Review Manage 5.3 was used for meta-analysis.
resultsSixteen studies involving 1050 patients (464 patients in the MIPO group and 586 patients in the ORIF group) were finally included. According to the meta-analysis, MIPO was superior to ORIF in operation time, blood loss, postoperative pain, fracture union time, and constant score. However, MIPO was associated with more exposure to radiation and axillary nerve injury. No significant differences were found in length of hospital stays and complication except for axillary nerve injury.
conclusionThe present evidence indicates that compared to ORIF, MIPO had advantages in functional outcomes, operation time, blood loss, postoperative pain, and fracture union time for the treatment of PHFs. However, the MIPO technique had a higher rate of axillary nerve injury and longer radiation time compared to ORIF.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.