Evidence map›Paper›PMID 31739799›Full record

SynthesisDiagnostic pathology2019

Uterine lesions with sex cord-like architectures: a systematic review.

Meng Jia, Ping-Li Sun, Hongwen Gao

Abstract readSystematic Review
In one paragraph

Synthesis in Diagnostic pathology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Meng JiaDepartment of pathology, The Second Hospital of Jilin University, Changchun, Jilin, 130041, China.
Ping-Li SunDepartment of pathology, The Second Hospital of Jilin University, Changchun, Jilin, 130041, China. pinglisun@naver.com.ORCID http://orcid.org/0000-0002-7511-3080
Hongwen GaoDepartment of pathology, The Second Hospital of Jilin University, Changchun, Jilin, 130041, China. gaohw@jlu.edu.cn.

Funding

Science and Technology Development Project of Jilin Province 3D5177723429Science and Technology of Jilin Province, Jilin Province Key Laboratory 3D517K363429The Role and Molecular Mechanism of EMT in the Resistance of ROS1-positive Lung Cancer 20180101014JC
6 · The paper itself

Abstract

backgroundSex cord-like elements are rarely observed in uterine lesions, but these morphological patterns could appear in a variety of uterine tumors and non-tumorous lesions. In this review, we collected the literatures regarding the uterine tumorous and non-tumorous lesions containing sex cord-like elements and summarized these lesions in terms of clinicopathological, immunohistochemical, and molecular features in order to further understand these lesions and provide some new ideas for differential diagnosis. MAIN BODY: This section provides a comprehensive overview of the clinicopathological, immunohistochemical, and molecular features of uterine lesions with sex cord-like architectures including uterine tumors resembling ovarian sex cord tumors, endometrial stromal tumors, adenomyosis, endometrial polyps, leiomyoma, epithelioid leiomyosarcoma, adenosarcoma, sertoliform endometrioid carcinoma, corded and hyalinized endometrioid carcinoma, mesonephric adenocarcinoma, and mesonephric-like adenocarcinoma. The differential diagnosis based on morphology, immunohistochemistry, and molecular alterations has also been discussed.

conclusionThe sex cord-like areas in these lesions show heterogeneous but similar morphological features. Additionally, immunohistochemical staining plays a limited role in differential diagnosis. Furthermore, it is of significance for pathologists to better understand these lesions in order to avoid confusion and mistakes during pathological diagnosis, especially in a biopsy/curettage specimen.

Indexed as

AdenocarcinomaCarcinoma, EndometrioidFemaleHumansOvarian NeoplasmsSex Cord-Gonadal Stromal TumorsUterine Cervical NeoplasmsUterine NeoplasmsEndometrial stromal tumorImmunohistochemistrySex cordUterineUTROSCT

Identifiers

PMID31739799
PMCPMC6862816

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.