ArticleCirculation research2020
Functional Screening of Candidate Causal Genes for Insulin Resistance in Human Preadipocytes and Adipocytes.
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In one paragraph
Article in Circulation research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 1 pooled it
6.4field-weighted citation impact, top 3% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
48 citing papers in PubMed, 1 synthesis or guideline pooled it, 83 citations in OpenAlex.
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- Cell type-specific epigenetic regulatory circuitry of coronary artery disease loci.Nature communications · 2026Article
- Genetic insights and mechanistic parallels in gestational diabetes mellitus and type 2 diabetes.Nature communications · 2026Article
- Fructose and follistatin potentiate acute MASLD during complete hepatic insulin resistance.Nature communications · 2025Article
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- Genetic Architecture and Clinical Outcomes of Combined Lipid Disturbances.Circulation research · 2024Article
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Corrections and comments
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Authors and funding
13 authors at 6 institutions in 2 countries.
Zhifen ChenFrom the Beth Israel Deaconess Medical Center, Cardiovascular Institute, Harvard Medical School, Boston, MA (Z.C., H.Y., X.S., M.F., T.B.M., M.D.B., R.E.G, C.A.C.).
Haojie YuFrom the Beth Israel Deaconess Medical Center, Cardiovascular Institute, Harvard Medical School, Boston, MA (Z.C., H.Y., X.S., M.F., T.B.M., M.D.B., R.E.G, C.A.C.).
Xu ShiFrom the Beth Israel Deaconess Medical Center, Cardiovascular Institute, Harvard Medical School, Boston, MA (Z.C., H.Y., X.S., M.F., T.B.M., M.D.B., R.E.G, C.A.C.).
Curtis R WarrenHarvard Stem Cell Institute, Harvard University, Cambridge, MA (Z.C., H.Y., M.F., C.R.W., T.B.M., C.A.C.).
Luca A LottaMRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom (L.A.L., C.L., N.W.).
Max FriesenFrom the Beth Israel Deaconess Medical Center, Cardiovascular Institute, Harvard Medical School, Boston, MA (Z.C., H.Y., X.S., M.F., T.B.M., M.D.B., R.E.G, C.A.C.).
Torsten B MeissnerFrom the Beth Israel Deaconess Medical Center, Cardiovascular Institute, Harvard Medical School, Boston, MA (Z.C., H.Y., X.S., M.F., T.B.M., M.D.B., R.E.G, C.A.C.).
Claudia LangenbergMRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom (L.A.L., C.L., N.W.).
Martin WabitschPediatrics and Adolescent Medicine, Ulm University Hospital, Germany (M.W.).
Nick WarehamMRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom (L.A.L., C.L., N.W.).
Mark D BensonFrom the Beth Israel Deaconess Medical Center, Cardiovascular Institute, Harvard Medical School, Boston, MA (Z.C., H.Y., X.S., M.F., T.B.M., M.D.B., R.E.G, C.A.C.).
Rob E GersztenFrom the Beth Israel Deaconess Medical Center, Cardiovascular Institute, Harvard Medical School, Boston, MA (Z.C., H.Y., X.S., M.F., T.B.M., M.D.B., R.E.G, C.A.C.).
Chad A CowanFrom the Beth Israel Deaconess Medical Center, Cardiovascular Institute, Harvard Medical School, Boston, MA (Z.C., H.Y., X.S., M.F., T.B.M., M.D.B., R.E.G, C.A.C.).
Beth Israel Deaconess Medical Center · USHarvard Stem Cell Institute · USHarvard University · USMRC Epidemiology Unit · GBBoehringer Ingelheim (United States) · USUniversity of Cambridge · GB
Funding
ROLE OF DIETARY CONSTITUENTS ON GENE EXPRESSION IN INTESTINAL EPITHELIUMP30DK040561 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI CHRISTOPHER P DUGGAN · 1994 to 2026
$31.6MProposal for the AMP T2D-GENES Data Coordination Center and Web PortalU01DK105554 · NIDDK · BROAD INSTITUTE, INC. · PI FLOREZ, JOSE CARLOS · 2015 to 2019
$16.8MA National iPS Cell Network with Deep Phenotyping for Translational ResearchU01TR001810 · NCATS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI GILAD, YOAV, KOTTON, DARRELL N. · 2016 to 2020
$4.4MThe Role of PPM1G in Apolipoprotein E Biology and Atherosclerotic Cardiovascular DiseaseK08HL145095 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI BENSON, MARK DANIEL · 2019 to 2023
$836kMedical Research Council MC_UU_12015/1NCATS NIH HHS U01 TR001810NHLBI NIH HHS K08 HL145095NIDDK NIH HHS P30 DK040561NIDDK NIH HHS U01 DK105554
Abstract
PubMed holds no abstract for this paper.
Indexed as
Quantitative Trait LociAdaptor Proteins, Signal TransducingAdipocytesCell LineDipeptidasesFollistatinGenome-Wide Association StudyHumansInsulin Receptor Substrate ProteinsInsulin ResistanceLoss of Function MutationLymphokinesMAP Kinase Kinase Kinase 1Platelet-Derived Growth FactorPPAR gammaAdaptor Proteins, Signal TransducingDipeptidasesFollistatinFST protein, humanGRB14 protein, humanInsulin Receptor Substrate ProteinsIRS1 protein, humanLymphokinesMAP3K1 protein, humanMAP Kinase Kinase Kinase 1PEPD protein, humanPlatelet-Derived Growth Factorplatelet-derived growth factor CPPAR gammaPPARG protein, humanadipocytesadipogenesisdiabetes mellitus, type 2insulin resistancelipid metabolis
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.