Evidence map›Paper›PMID 31739506›Full record

ArticleJournal of clinical medicine2019

Microbiota Dysbiosis in Fungal Rhinosinusitis.

Yen-Ting Lu, Shao-Hung Wang, Ming-Li Liou, Ting-An Shen, Ying-Chou Lu, Chung-Han Hsin, Shun-Fa Yang, Yih-Yuan Chen, Tzu-Hao Chang

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. The microbiome of the nasopharynx.Journal of medical microbiology · 2021
    Review
  8. Article
  9. Review
  10. Microbial Dysbiosis in Nasopharyngeal Carcinoma: A Pilot Study on Biomarker Potential.Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Yen-Ting LuDepartment of Otolaryngology, St. Martin De Porres Hospital, Chiayi 600, Taiwan.
Shao-Hung WangDepartment of Microbiology, Immunology and Biopharmaceuticals, National Chiayi University, Chiayi 600, Taiwan.ORCID 0000-0002-6824-0372
Ming-Li LiouDepartment of Medical Laboratory Science and Biotechnology, Yuanpei University, Hsin-Chu City 300, Taiwan.
Ting-An ShenGraduate Institute of Biomedical Informatics, Taipei Medical University, Taipei City 110, Taiwan.
Ying-Chou LuDepartment of Otolaryngology, St. Martin De Porres Hospital, Chiayi 600, Taiwan.
Chung-Han HsinDepartment of Otolaryngology, Chung Shan Medical University Hospital, Taichung 402, Taiwan.
Shun-Fa YangInstitute of Medicine, Chung Shan Medical University, Taichung 402, Taiwan.ORCID 0000-0002-0365-7927
Yih-Yuan ChenDepartment of Biochemical Science and Technology, National Chiayi University, Chiayi 600, Taiwan.
Tzu-Hao ChangGraduate Institute of Biomedical Informatics, Taipei Medical University, Taipei City 110, Taiwan.ORCID 0000-0001-7011-3754
Chung Shan Medical University Hospital · TWNational Chiayi University · TWTaipei Medical University · TWTaipei Medical University Hospital · TWYuanpei University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fungal rhinosinusitis is a unique phenotype of chronic rhinosinusitis with unique clinical and histological characteristics. The role of bacterial microbiota in various phenotypes chronic rhinosinusitis is not thoroughly understood. Therefore, we conducted 16s rRNA amplification sequencing to determine differences in bacterial communities between phenotypes (fungal vs. non- fungal) and anatomical sites (middle meatus vs. nasopharynx). Endoscope-guided swabs were used to collect samples from the middle meatus and nasopharynx of seven consecutive patients with fungal and 18 consecutive patients with non-fungal rhinosinusitis. DNA was extracted and investigated through 16S rRNA amplification. Among samples from the middle meatus, Shannon diversity was significantly lower in those from the fungal rhinosinusitis group (

Indexed as

16srRNAchronic rhinosinusitisdysbiosisfungal rhinosinusitismicrobiomemicrobiotanext-generation sequencingnon-fungal rhinosinusitis

Identifiers

PMID31739506
PMCPMC6912393
OpenAlexW2987502492

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.