Evidence map›Paper›PMID 31739505›Full record

ArticleJournal of clinical medicine2019

Impact of Pregnancy on Intra-Host Genetic Diversity of Influenza A Viruses in Hospitalised Women: A Retrospective Cohort Study.

Gregory Destras, Maxime Pichon, Bruno Simon, Martine Valette, Vanessa Escuret, Pierre-Adrien Bolze, Gil Dubernard, Pascal Gaucherand, Bruno Lina, Laurence Josset

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Pharmacological inhibition of poly (ADP-ribose) polymerase by olaparib ameliorates influenza-virus-induced pneumonia in mice.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2021
    Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Gregory DestrasVirpath, INSERM U1111, CNRS UMR5308, International Center for Infectiology Research, ENS Lyon, Claude Bernard Lyon 1 University, 69008 Lyon, France.
Maxime PichonVirpath, INSERM U1111, CNRS UMR5308, International Center for Infectiology Research, ENS Lyon, Claude Bernard Lyon 1 University, 69008 Lyon, France.ORCID 0000-0002-3732-6894
Bruno SimonVirology Laboratory, Infectious Agents Institute, CBN, Groupement Hospitalier Nord, Hospices Civils de Lyon, 69004 Lyon, France.ORCID 0000-0001-9054-3946
Martine ValetteVirology Laboratory, Infectious Agents Institute, CBN, Groupement Hospitalier Nord, Hospices Civils de Lyon, 69004 Lyon, France.
Vanessa EscuretVirpath, INSERM U1111, CNRS UMR5308, International Center for Infectiology Research, ENS Lyon, Claude Bernard Lyon 1 University, 69008 Lyon, France.
Pierre-Adrien BolzeService de Chirurgie Gynécologique et Oncologique-Obstétrique, Centre Hospitalier Lyon Sud, Hospices Civils de Lyon, 69310 Pierre-Bénite, France.
Gil DubernardHospices Civils de Lyon, Service de Gynécologie et d'Obstétrique, Hôpital de la Croix Rousse, 69004 Lyon, France.
Pascal GaucherandConsultation Obstétrique, Groupement Hospitalier Est, Hospices Civils de Lyon, 69500 Bron, France.
Bruno LinaVirpath, INSERM U1111, CNRS UMR5308, International Center for Infectiology Research, ENS Lyon, Claude Bernard Lyon 1 University, 69008 Lyon, France.ORCID 0000-0002-8959-2123
Laurence JossetVirpath, INSERM U1111, CNRS UMR5308, International Center for Infectiology Research, ENS Lyon, Claude Bernard Lyon 1 University, 69008 Lyon, France.ORCID 0000-0002-7158-1186
Université Claude Bernard Lyon 1 · FRHospices Civils de Lyon · FRHôpital de la Croix-Rousse · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Characterising dynamics of Influenza A Viruses (IAV) within-host evolution is an active field of research which may lead to a better understanding of viral pathogenesis. Using a pregnant mouse model, a study has recently suggested that immune modulation during pregnancy could promote the emergence of IAV quasispecies with increased virulence. Herein, we assess the clinical relevance of these findings in humans. We studied IAV intra-host diversity (ihD) in pregnant (

Indexed as

influenzapregnancyquasispeciesultra-deep sequencingviral diversity

Identifiers

PMID31739505
PMCPMC6912736
OpenAlexW2984464927

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.