Evidence map›Paper›PMID 31739454›Full record

ArticleAntibiotics (Basel, Switzerland)2019

Investigations into the Structure/Antibacterial Activity Relationships of Cyclam and Cyclen Derivatives.

Luis G Alves, João F Portel, Sílvia A Sousa, Olga Ferreira, Stephanie Almada, Elisabete R Silva, Ana M Martins, Jorge H Leitão

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. New Cyclam-Based Fe(III) Complexes Coatings TargetingMolecules (Basel, Switzerland) · 2025
    Article
  3. Article
  4. Disclosing the Antifungal Mechanisms of the Cyclam Salt HInternational journal of molecular sciences · 2024
    Article
  5. A Cyclam Salt as an Antifungal Agent: Interference withAntibiotics (Basel, Switzerland) · 2024
    Article
  6. Review
  7. Crystal structure of di-aqua-(3,14-diethyl-2,6,13,17-tetra-aza-tri-cyclo-[16.4.0.0Acta crystallographica. Section E, Crystallographic communications · 2021
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Luis G AlvesCentro de Química Estrutural, Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, 1049-003 Lisboa, Portugal.
João F PortelIBB-Instituto de Bioengenharia e Biociências, Instituto Superior Técnico, Universidade de Lisboa, 1049-001 Lisboa, Portugal.
Sílvia A SousaIBB-Instituto de Bioengenharia e Biociências, Instituto Superior Técnico, Universidade de Lisboa, 1049-001 Lisboa, Portugal.ORCID 0000-0001-9291-9169
Olga FerreiraBioISI-Biosystems & Integrative Sciences Institute, Faculdade de Ciências da Universidade de Lisboa, Campo Grande, 1749-016 Lisboa, Portugal.
Stephanie AlmadaCentro de Química Estrutural, Instituto Superior Técnico, Universidade de Lisboa, 1049-001 Lisboa, Portugal.
Elisabete R SilvaBioISI-Biosystems & Integrative Sciences Institute, Faculdade de Ciências da Universidade de Lisboa, Campo Grande, 1749-016 Lisboa, Portugal.ORCID 0000-0001-6679-4374
Ana M MartinsCentro de Química Estrutural, Instituto Superior Técnico, Universidade de Lisboa, 1049-001 Lisboa, Portugal.ORCID 0000-0002-3922-5501
Jorge H LeitãoIBB-Instituto de Bioengenharia e Biociências, Instituto Superior Técnico, Universidade de Lisboa, 1049-001 Lisboa, Portugal.ORCID 0000-0001-8850-274X
University of Lisbon · PTIST-ID - Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento

Funding

Fundação para a Ciência e a Tecnologia UID/BIO/04565/2019Fundação para a Ciência e a Tecnologia UI/QUI/0100/2019Programa Operacional Regional de Lisboa 2020 N.007317
6 · The paper itself

Abstract

A series of cyclam- and cyclen-derived salts are described in the present work; they were designed specifically to gain insights into their structure and antibacterial activity towards

Indexed as

AntibacterialsAzaringsE. coliS. aureustetraazamacrocycles

Identifiers

PMID31739454
PMCPMC6963676
OpenAlexW2986360110

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.