ArticleInternational journal of molecular sciences2019
Provitamin A Biofortification of Durum Wheat through a TILLING Approach.
Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 36 citations in OpenAlex.
- Comparative Analysis of Phytochemical Composition and Antioxidant Activity of Sprouts from Eight Hemp (Foods (Basel, Switzerland) · 2026Article
- Review
- Esterification enhances carotenoid retention during bread-making.Journal of the science of food and agriculture · 2026Article
- Gene-Editing-Mediated Enhancement of Carotenoid Compound Accumulation in Common Wheat Grains.Foods (Basel, Switzerland) · 2026Article
- Grain yellowness is an effective predictor of carotenoid content in global sorghum populations.Scientific reports · 2024Article
- The suppression of TdMRP3 genes reduces the phytic acid and increases the nutrient accumulation in durum wheat grain.Frontiers in plant science · 2023Article
- Biofortification to avoid malnutrition in humans in a changing climate: Enhancing micronutrient bioavailability in seed, tuber, and storage roots.Frontiers in plant science · 2023Review
- Is it the end of TILLING era in plant science?Frontiers in plant science · 2023Review
- Gene Expression Analyses Reveal Mechanisms of Inhibited Yellowing by Applying Selenium-Chitosan on Fresh-Cut Broccoli.Foods (Basel, Switzerland) · 2022Article
- Mutant combinations of lycopene ɛ-cyclase and β-carotene hydroxylase 2 homoeologs increased β-carotene accumulation in endosperm of tetraploid wheat (Triticum turgidum L.) grains.Plant biotechnology journal · 2022Article
- Gene Editing to Accelerate Crop Breeding.Frontiers in plant science · 2022Article
- Enrichment of provitamin A content in durum wheat grain by suppressing β-carotene hydroxylase 1 genes with a TILLING approach.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2021Article
- Vitamins in Cereals: A Critical Review of Content, Health Effects, Processing Losses, Bioaccessibility, Fortification, and Biofortification Strategies for Their Improvement.Frontiers in nutrition · 2021Review
- Unveiling the Genetic and Physiological Synergies of Iron and Sulfur Homeostasis in Durum Wheat: From Root to Grain.Physiologia plantarumArticle
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
Macro- and micronutrients, essential for the maintenance of human metabolism, are assimilated daily through the diet. Wheat and other major cereals are a good source of nutrients, such as carbohydrates and proteins, but cannot supply a sufficient amount of essential micronutrients, including provitamin A. As vitamin A deficiency (VAD) leads to several serious diseases throughout the world, the biofortification of a major staple crop, such as wheat, represents an effective way to preserve human health in developing countries. In the present work, a key enzyme involved in the branch of carotenoids pathway producing β-carotene, lycopene epsilon cyclase, has been targeted by a Targeting Induced Local Lesions in Genomes (TILLING) approach in a "block strategy" perspective. The null mutant genotype showed a strong reduction in the expression of the
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Registered trials
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