Evidence map›Paper›PMID 31739432›Full record

ArticleViruses2019

Zika Virus Dissemination from the Midgut of

Yingjun Cui, DeAna G Grant, Jingyi Lin, Xiudao Yu, Alexander W E Franz

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
  2. Review
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  8. Article
  9. Transcriptome analysis ofCurrent research in parasitology & vector-borne diseases · 2025
    Article
  10. Article
  11. Cytoskeleton-associated gelsolin responds to the midgut distention process in saline meal-fed Aedes aegypti and affects arbovirus dissemination from the midgut.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Mechanisms of Zika astrocyte infection and neuronal toxicity.NeuroImmune pharmacology and therapeutics · 2023
    Article
  16. Factors Affecting Arbovirus Midgut Escape in Mosquitoes.Pathogens (Basel, Switzerland) · 2023
    Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Yingjun CuiDepartment of Veterinary Pathobiology, University of Missouri, Columbia, MO 65211, USA.ORCID 0000-0002-7416-0934
DeAna G GrantElectron Microscopy Core Facility, University of Missouri, Columbia, MO 65211, USA.
Jingyi LinDepartment of Veterinary Pathobiology, University of Missouri, Columbia, MO 65211, USA.
Xiudao YuDepartment of Veterinary Pathobiology, University of Missouri, Columbia, MO 65211, USA.
Alexander W E FranzDepartment of Veterinary Pathobiology, University of Missouri, Columbia, MO 65211, USA.
University of Missouri · US

Funding

How Do Arboviruses Escape the Mosquito Midgut?- Analysis of a Novel MechanismR01AI134661 · NIAID · UNIVERSITY OF MISSOURI-COLUMBIA · PI FRANZ, ALEXANDER W E · 2018 to 2022
$1.9M
NIAID NIH HHS R01 AI134661NIH HHS 1R01AI134661
6 · The paper itself

Abstract

The arboviral disease cycle requires that key tissues in the arthropod vector become persistently infected with the virus. The midgut is the first organ in the mosquito that needs to be productively infected with an orally acquired virus. Following midgut infection, the virus then disseminates to secondary tissues including the salivary glands. Once these are productively infected, the mosquito is able to transmit the virus to a vertebrate host. Recently, we described the midgut dissemination pattern for chikungunya virus in

Indexed as

AedesAnimalsBasement MembraneDengue VirusFemaleGastrointestinal TractMosquito VectorsViral LoadViral Plaque AssayZika VirusZika Virus Infectionbasal laminaconsecutive bloodmealsdengue 4 virusdisseminationelectron microscopyimmunofluorescence assaymidgutmosquitonanoparticlesZika virus

Identifiers

PMID31739432
PMCPMC6893695
OpenAlexW2988656621

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.