ReviewCurrent opinion in microbiology2019
Molecular regulation of Histoplasma dimorphism.
Review in Current opinion in microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 23 citations in OpenAlex.
- Polyphenism Through RNA Chemical Modifications.Molecular ecology · 2026Review
- Genome dynamics and chromosome structural variations in Histoplasma ohiense, a fungal pathogen of humans.G3 (Bethesda, Md.) · 2026Article
- The dynamics of transposable element content in the genome of the human pathogen Histoplasma.Fungal genetics and biology : FG & B · 2026Article
- Hidden Histoplasmosis: Adrenal and Central Nervous System Mycosis in an Immunocompetent Patient.Cureus · 2025Article
- Signaling Pathways Regulating Dimorphism in Medically Relevant Fungal Species.Pathogens (Basel, Switzerland) · 2025Review
- Tracing histoplasmosis genomic epidemiology and species occurrence across the USA.Emerging microbes & infections · 2024Article
- Development of a TaqMan probe-based multiplex real-time PCR for the simultaneous detection of four clinically important filamentous fungi.Microbiology spectrum · 2024Article
- Fruiting Body Heterogeneity, Dimorphism and Haustorium-like Structure ofJournal of fungi (Basel, Switzerland) · 2024Article
- Genotypic diversity, virulence, and molecular genetic tools inMicrobiology and molecular biology reviews : MMBR · 2024Review
- Common virulence factors betweenCurrent research in microbial sciences · 2024Review
- Antifungal Activity of Chitosan againstJournal of fungi (Basel, Switzerland) · 2023Article
- Targeted gene deletions in the dimorphic fungal pathogenmSphere · 2023Article
- Response and regulatory mechanisms of heat resistance in pathogenic fungi.Applied microbiology and biotechnology · 2022Review
- An Indian lineage of Histoplasma with strong signatures of differentiation and selection.Fungal genetics and biology : FG & B · 2022Article
- Diversification of Fungal Chitinases and Their Functional Differentiation in Histoplasma capsulatum.Molecular biology and evolution · 2021Article
- Fungal Pathogens: Shape-Shifting Invaders.Trends in microbiology · 2020Review
- Role of Cell Surface Hydrophobicity in the Pathogenesis of Medically-Significant Fungi.Frontiers in cellular and infection microbiology · 2020Review
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Temperature serves as a fundamental signal in biological systems. In some microbial pathogens of humans, mammalian body temperature triggers establishment and maintenance of a developmental program that allows the microbe to survive and thrive in the host. Histoplasma capsulatum is one of a group of fungal pathogens called thermally dimorphic fungi, all of which respond to mammalian body temperature by converting from an environmental mold form that inhabits the soil into a parasitic form that causes disease in the host. It has been known for decades that temperature is a key signal that is sufficient to trigger the switch from the soil to host form (and vice versa) in the laboratory. Recent molecular studies have identified a number of key regulators that are required to specify each of the developmental forms in response to temperature. Here we review the regulatory circuits that govern temperature-dependent dimorphism in Histoplasma.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.