ArticleAtherosclerosis2020
Body mass index and peripheral artery disease.
Article in Atherosclerosis, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 54 citations in OpenAlex.
- Interaction between adiposity and genetic risk score on blood pressure traits in Mexican adults.Journal of human hypertension · 2026Article
- The Impact of Glucagon-like Peptide-1 Receptor Agonists on Cardiovascular-Kidney-Metabolic Health in Romanian Patients with Type 2 Diabetes: A Retrospective Study.Journal of clinical medicine · 2025Article
- A computational framework for defining and validating reproducible phenotyping algorithms of 313 diseases in the UK Biobank.Scientific reports · 2025Article
- The relationship between weight-adjusted waist index and peripheral artery disease.Frontiers in nutrition · 2025Article
- Development and validation of a nomogram for predicting the risk of postoperative fracture blister after pilon fracture.Frontiers in surgery · 2024Article
- Risk factors and predictive model construction for lower extremity arterial disease in diabetic patients.PloS one · 2024Article
- Association between oxidative balance scores and peripheral artery disease in US adults: a cross-sectional study.Frontiers in nutrition · 2024Article
- Association of erectile dysfunction and peripheral arterial disease in NHANES 2001-2004: a cross-sectional study.Frontiers in endocrinology · 2024Article
- Assessment of causal associations between obesity and peripheral artery disease: a bidirectional Mendelian randomization study.Frontiers in cardiovascular medicine · 2024Article
- Neutrophil-to-lymphocyte ratio in type 2 diabetes patients combined with Lower Extremity Peripheral Artery Disease.Frontiers in endocrinology · 2024Article
- Diet-induced obesity augments ischemic myopathy and functional decline in a murine model of peripheral artery disease.Translational research : the journal of laboratory and clinical medicine · 2023Article
- Role of obesity related inflammation in pathogenesis of peripheral artery disease in patients of type 2 diabetes mellitus.Journal of diabetes and metabolic disorders · 2023Review
- Focus on the Prevention of Acute Limb Ischemia: Centrality of the General Practitioner from the Point of View of the Internist.Journal of clinical medicine · 2023Review
- Article
- Different associations of general and abdominal obesity with upper and lower extremity artery disease among a community population in China.Nutrition & metabolism · 2023Article
- Article
- Mortality Risk Assessment in Peripheral Arterial Disease-The Burden of Cardiovascular Risk Factors over the Years: A Single Center's Experience.Diagnostics (Basel, Switzerland) · 2022Article
- Dietary Risk Factors and Eating Behaviors in Peripheral Arterial Disease (PAD).International journal of molecular sciences · 2022Review
- Genetic evidence for a causal relationship between type 2 diabetes and peripheral artery disease in both Europeans and East Asians.BMC medicine · 2022Article
- Comparison of waist-height ratio and other obesity indices in the prediction of diabetic peripheral neuropathy.Frontiers in nutrition · 2022Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
BACKGROUND AND
aimsAn independent association of body mass index (BMI) with atherosclerotic cardiovascular disease is somewhat controversial and may differ by vascular bed. Sex-specific risk factors for atherosclerosis may further modify these associations. Obesity and peripheral artery disease (PAD) are both more prevalent in women. We sought to determine the association between PAD and BMI using a very large population-based study.
methodsSelf-referred individuals at >20,000 US sites completed medical questionnaires including height and weight, and were evaluated by screening ankle brachial indices (ABI) for PAD (ABI<0.9).
resultsAmong 3,250,350 individuals, the mean age was 63.1 ± 10.5 years and 65.5% were women. The mean BMI was 27.7 ± 5.8 kg/m
conclusionsOur study suggests that increasing BMI is a robust independent risk factor for PAD only in women. This observation requires validation, but highlights the need for further research on sex-specific risk and mechanisms of atherosclerosis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.