Evidence map›Paper›PMID 31737992›Full record

ReviewBiological reviews of the Cambridge Philosophical Society2020

Post-ejaculatory modifications to sperm (PEMS).

Scott Pitnick, Mariana F Wolfner, Steve Dorus

Abstract readReview
In one paragraph

Review in Biological reviews of the Cambridge Philosophical Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Seminal Vesicle-Derived Exosomes for the Regulation of Sperm Activity.Advances in anatomy, embryology, and cell biology · 2026
    Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Drosophila melanogaster sperm turn more oxidative in the female.The Journal of experimental biology · 2024
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Scott PitnickDepartment of Biology, Center for Reproductive Evolution, Syacuse University, Syracuse, NY, 13244, USA.ORCID 0000-0002-8973-6166
Mariana F WolfnerDepartment of Molecular Biology and Genetics, Cornell University, Ithaca, NY, 14853, USA.ORCID 0000-0003-2701-9505
Steve DorusDepartment of Biology, Center for Reproductive Evolution, Syacuse University, Syracuse, NY, 13244, USA.ORCID 0000-0002-2666-9947

Funding

ACTIONS OF SEMINAL PROTEINS IN MATED DROSOPHILA FEMALESR01HD038921 · NICHD · CORNELL UNIVERSITY ITHACA · PI WOLFNER, MARIANA FEDERICA · 2000 to 2019
$5.6M
Sperm Motility and Molecular Interactions in the Reproductive Tract R21HD088910 · NICHD · SYRACUSE UNIVERSITY · PI DORUS, STEPHEN · 2017 to 2018
$433k
NICHD NIH HHS R01 HD038921NICHD NIH HHS R21 HD088910
6 · The paper itself

Abstract

Mammalian sperm must spend a minimum period of time within a female reproductive tract to achieve the capacity to fertilize oocytes. This phenomenon, termed sperm 'capacitation', was discovered nearly seven decades ago and opened a window into the complexities of sperm-female interaction. Capacitation is most commonly used to refer to a specific combination of processes that are believed to be widespread in mammals and includes modifications to the sperm plasma membrane, elevation of intracellular cyclic AMP levels, induction of protein tyrosine phosphorylation, increased intracellular Ca

Indexed as

Acrosome ReactionAnimalsEjaculationMaleSpermatozoaSperm Capacitationcapacitationfemale reproductive tractfertilityhyperactivationmorphogenesismotilitypost-copulatory sexual selectionseminal proteinsspermatozoasperm competition

Identifiers

PMID31737992
PMCPMC7643048

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.