ArticleJournal of magnetic resonance imaging : JMRI2020
Scan-Rescan Repeatability and Impact of B
Article in Journal of magnetic resonance imaging : JMRI, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 23 citations in OpenAlex.
- MRI-Based Quantitative Assessment of Normal-Appearing White and Gray Matter Demyelination in Multiple Sclerosis, Parkinson's Disease, Long COVID, and Normal Aging.Biomedicines · 2026Article
- Macromolecular Proton Fraction Reveals Divergent White Matter Myelination in Bipolar Disorder and Unipolar Recurrent Depression.Bioengineering (Basel, Switzerland) · 2026Article
- Demyelination and Cognitive Performance in Long COVID Patients with Insomnia and/or Depression.International journal of molecular sciences · 2025Article
- Assessment of Trigeminal Nerve Root Demyelination in Patients with Primary Trigeminal Neuralgia Using Macromolecular Proton Fraction Imaging.AJNR. American journal of neuroradiology · 2025Article
- Single-point macromolecular proton fraction mapping using a 0.3 T permanent magnet MRI system: phantom and healthy volunteer study.Radiological physics and technology · 2024Article
- Global and Regional Sex-Related Differences, Asymmetry, and Peak Age of Brain Myelination in Healthy Adults.Journal of clinical medicine · 2024Article
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- Macromolecular Proton Fraction as a Myelin Biomarker: Principles, Validation, and Applications.Frontiers in neuroscience · 2022Review
- Language input in late infancy scaffolds emergent literacy skills and predicts reading related white matter development.Frontiers in human neuroscience · 2022Article
- Data-Driven Retrospective Correction of BIEEE transactions on medical imaging · 2021Article
- Long-term monitoring of chronic demyelination and remyelination in a rat ischemic stroke model using macromolecular proton fraction mapping.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021Article
- Global hypomyelination of the brain white and gray matter in schizophrenia: quantitative imaging using macromolecular proton fraction.Translational psychiatry · 2021Article
- Myelin development in cerebral gray and white matter during adolescence and late childhood.NeuroImage · 2021Article
- Three-dimensional fast single-point macromolecular proton fraction mapping of the human brain at 0.5 Tesla.Quantitative imaging in medicine and surgery · 2020Article
- Quantitative Multi-Parameter Mapping Optimized for the Clinical Routine.Frontiers in neuroscience · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 2 countries.
Funding
Abstract
backgroundSingle-point macromolecular proton fraction (MPF) mapping is a recent quantitative MRI method for fast assessment of brain myelination. Information about reproducibility and sensitivity of MPF mapping to magnetic field nonuniformity is important for clinical applications. PURPOSE: To assess scan-rescan repeatability and a value of B STUDY TYPE: Prospective. POPULATION: Eight healthy adult volunteers underwent two scans with 11.5 ± 2.3 months interval. FIELD STRENGTH/SEQUENCE: 3T; whole-brain 3D MPF mapping protocol included three spoiled gradient-echo sequences providing T ASSESSMENT: MPF maps were reconstructed with B STATISTICAL TESTS: Within-subject coefficient of variation (CV), intraclass correlation coefficient (ICC), Bland-Altman plots, and paired t-tests to assess scan-rescan repeatability. Repeated-measures analysis of variance (ANOVA) to compare field corrections.
resultsMaximal relative local MPF errors without correction in the areas of largest field nonuniformities were about 5% and 27% for B DATA
conclusionThe single-point method enables high repeatability of MPF maps obtained with the same equipment. Correction of B LEVEL OF EVIDENCE: 2 Technical Efficacy: Stage 1 J. Magn. Reson. Imaging 2020;51:1789-1798.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.