Evidence map›Paper›PMID 31737935›Full record

ArticleMagnetic resonance in medicine2020

Removing rician bias in diffusional kurtosis of the prostate using real-data reconstruction.

Rosie J Goodburn, Tristan Barrett, Ilse Patterson, Ferdia A Gallagher, Edward M Lawrence, Vincent J Gnanapragasam, Christof Kastner, Andrew N Priest

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rosie J GoodburnDepartment of Medical Physics, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.ORCID 0000-0001-5109-4738
Tristan BarrettDepartment of Radiology, School of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom.
Ilse PattersonDepartment of Radiology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.
Ferdia A GallagherDepartment of Radiology, School of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom.
Edward M LawrenceDepartment of Radiology, School of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom.
Vincent J GnanapragasamAcademic Urology Group, Department of Surgery, University of Cambridge, Cambridge, United Kingdom.
Christof KastnerDepartment of Urology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.
Andrew N PriestDepartment of Radiology, School of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom.

Funding

Cancer Research UK 16628Cancer Research UK 27150Cancer Research UK C19212/A16628Department of Health
6 · The paper itself

Abstract

purposeTo compare prostate diffusional kurtosis imaging (DKI) metrics generated using phase-corrected real data with those generated using magnitude data with and without noise compensation (NC).

methodsDiffusion-weighted images were acquired at 3T in 16 prostate cancer patients, measuring 6 b-values (0-1500 s/mm

resultsSimulations indicated LPF size can strongly affect K metrics, where 64-pixel LPFs produced accurate metrics. Relative to metrics estimated from magnitude data without NC, median NC K were lower (P < 0.0001) by 6/11/8% in tumor/NPZ/NTZ, 64-LPF real-data K were lower (P < 0.0001) by 4/10/7%, respectively.

conclusionCompared with magnitude data with NC, phase-corrected real data can produce similar K, although the choice of phase-correction LPF should be chosen carefully.

Indexed as

Diffusion Magnetic Resonance ImagingProstatic NeoplasmsDiffusionDiffusion Tensor ImagingHumansMalediffusional kurtosis MRIdiffusion weighted MRIprostate cancerquantitative imaging

Identifiers

PMID31737935
PMCPMC7065237

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