Evidence map›Paper›PMID 31737826›Full record

ArticleACS omega2019

Studies Exploring the Interaction of the Organophosphorus Compound Paraoxon with Fullerenes.

Geraldine Magnin, Philippe Bissel, Roberto McAlister Council-Troche, Zhiguo Zhou, Marion Ehrich

Open access · goldAbstract read
In one paragraph

Article in ACS omega, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Geraldine MagninVirginia-Maryland College of Veterinary Medicine, Virginia Tech, Blacksburg, Virginia 24061, United States.
Philippe BisselVirginia-Maryland College of Veterinary Medicine, Virginia Tech, Blacksburg, Virginia 24061, United States.
Roberto McAlister Council-TrocheVirginia-Maryland College of Veterinary Medicine, Virginia Tech, Blacksburg, Virginia 24061, United States.
Zhiguo ZhouLuna Nanoworks, Danville, Virginia 24541, United States.
Marion EhrichVirginia-Maryland College of Veterinary Medicine, Virginia Tech, Blacksburg, Virginia 24061, United States.
Kansas State University · USVirginia–Maryland College of Veterinary Medicine · USMicron Corporation (United States) · US

Funding

Fullerenes Counteracting Organophosphorus ThreatsU01NS063723 · NINDS · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI EHRICH, MARION F · 2008 to 2010
$947k
NINDS NIH HHS U01 NS063723
6 · The paper itself

Abstract

In vitro experiments previously published demonstrated the ability of fullerenes to decrease the capability of organophosphorus (OP) compounds to inhibit acetylcholinesterase. Experiments described herein demonstrate molecular level affinity interactions between fullerenes and the OP test compound paraoxon with NMR spectroscopy. The calculated binding constant of 19 M

Identifiers

PMID31737826
PMCPMC6854557
OpenAlexW2982623765

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.