Evidence map›Paper›PMID 31737599›Full record

ReviewFrontiers in chemistry2019

Light-Induced Therapies for Prostate Cancer Treatment.

Claudia Ferroni, Alberto Del Rio, Cecilia Martini, Elisabetta Manoni, Greta Varchi

Abstract readReview
In one paragraph

Review in Frontiers in chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Review
  2. Review
  3. Integrative genomic analysis identifiesFrontiers in pharmacology · 2025
    Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. A Strategic Review on Carbon Quantum Dots for Cancer-Diagnostics and Treatment.Frontiers in bioengineering and biotechnology · 2022
    Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. X-ray tomography of cryopreserved human prostate cancer cells: mitochondrial targeting by an organoiridium photosensitiser.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Claudia FerroniInstitute of Organic Synthesis and Photoreactivity - ISOF, Italian National Research Council, Bologna, Italy.
Alberto Del RioInstitute of Organic Synthesis and Photoreactivity - ISOF, Italian National Research Council, Bologna, Italy.
Cecilia MartiniInstitute of Organic Synthesis and Photoreactivity - ISOF, Italian National Research Council, Bologna, Italy.
Elisabetta ManoniInstitute of Organic Synthesis and Photoreactivity - ISOF, Italian National Research Council, Bologna, Italy.
Greta VarchiInstitute of Organic Synthesis and Photoreactivity - ISOF, Italian National Research Council, Bologna, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prostate cancer (PC) is one of the most widespread tumors affecting the urinary system and the fifth-leading cause from cancer death in men worldwide. Despite PC mortality rates have been decreasing during the last years, most likely due to an intensification of early diagnosis, still more than 300,000 men die each year because of this disease. In this view, researchers in all countries are engaged in finding new ways to tackle PC, including the design and synthesis of novel molecular and macromolecular entities able to challenge different PC biological targets, while limiting the extent of unwanted side effects that significantly limit men's life quality. Among this field of research, photo-induced therapies, such as photodynamic and photothermal therapies (PDT and PTT), might represent an important advancement in PC treatment due to their extremely localized and controlled cytotoxic effect, as well as their low incidence of side effects and tumor resistance occurrence. Based on these considerations, this review aims to gather and discuss the last 5-years literature reports dealing with the synthesis and biological activity of molecular conjugates and nano-platforms for photo-induced therapies as co-adjuvant or combined therapeutic modalities for the treatment of localized PC.

Indexed as

lightnanoparticlesphotodynamic therapyphotothermal therapyprostate cancertargeted delivery

Identifiers

PMID31737599
PMCPMC6828976

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.