Evidence map›Paper›PMID 31737430›Full record

ArticleTranslational vision science & technology2019

The Role of Meibography in the Diagnosis of Meibomian Gland Dysfunction in Ocular Surface Diseases.

Mathieu Robin, Hong Liang, Ghislaine Rabut, Edouard Augstburger, Christophe Baudouin, Antoine Labbé

Open access · goldAbstract read
In one paragraph

Article in Translational vision science & technology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 27 citations in OpenAlex.

  1. The relationship between correction modality and clinical signs and symptoms of dry eye and meibomian gland dysfunction in keratoconic patients.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026
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  5. Internal validation of a convolutional neural network pipeline for assessing meibomian gland structure from meibography.Optometry and vision science : official publication of the American Academy of Optometry · 2025
    Article
  6. Review
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  8. Meibomian Gland Dysfunction Clinical Practice Guidelines.Japanese journal of ophthalmology · 2023
    Article
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  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Mathieu RobinDepartment of Ophthalmology 3, Quinze-Vingts National Ophthalmology Hospital, Paris, France.
Hong LiangDepartment of Ophthalmology 3, Quinze-Vingts National Ophthalmology Hospital, Paris, France.
Ghislaine RabutCHNO des Quinze-Vingts, IHU FOReSIGHT, INSERM-DGOS CIC 1423, Paris, France.
Edouard AugstburgerDepartment of Ophthalmology 3, Quinze-Vingts National Ophthalmology Hospital, Paris, France.
Christophe BaudouinDepartment of Ophthalmology 3, Quinze-Vingts National Ophthalmology Hospital, Paris, France.
Antoine LabbéDepartment of Ophthalmology 3, Quinze-Vingts National Ophthalmology Hospital, Paris, France.
Centre hospitalier national d'ophtalmologie des Quinze-Vingts · FRCentre National de la Recherche Scientifique · FRSorbonne Université · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate dysfunction in various ocular surface diseases (OSDs) including primary meibomian gland disease (MGD), perennial allergic conjunctivitis, and primary and secondary Sjögren syndromes.

methodsA retrospective analysis of 146 patients (111 women and 35 men) with symptomatic OSDs was performed. Patients were divided into two groups: the non-MGD group (55 patients) and the MGD group (91 patients). All patients had an evaluation of ocular surface symptoms and clinical tests, including tear film breakup time (BUT), the first and the mean noninvasive breakup time (NIKBUTf and NIKBUTavg, respectively). The meibomian gland loss of the lower eyelid was quantified using meibography and the meiboscale.

resultsThere was no significant difference regarding age or sex ratio between the two groups. The meiboscale in the MGD group was significantly higher than that in the non-MGD group (

conclusionsMeibomian gland dysfunction was observed among different OSDs. Meibomian gland loss evaluated by meibography might help identify MGD in patients suffering from OSD. TRANSLATION RELEVANCE: Meibography provides a better understanding of MGD in several OSD. It may be useful to integrate this objective analysis to improve treatments of OSD associated to MGD.

Indexed as

dry eye diseasemeibographymeibomian gland dysfunction

Identifiers

PMID31737430
PMCPMC6855297
OpenAlexW2987585467

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.