Evidence map›Paper›PMID 31737408›Full record

ArticleAdvances in wound care2019

Nanostructured Lipid Carriers of Pioglitazone Loaded Collagen/Chitosan Composite Scaffold for Diabetic Wound Healing.

Jawahar Natarajan, Bharat Kumar Reddy Sanapalli, Mehjabeen Bano, Sachin Kumar Singh, Monica Gulati, Veera Venkata Satyanarayana Reddy Karri

Abstract read
In one paragraph

Article in Advances in wound care, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 56 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jawahar NatarajanDepartment of Pharmaceutics, JSS College of Pharmacy, Ooty, JSS Academy of Higher Education and Research, India.
Bharat Kumar Reddy SanapalliDepartment of Pharmacology, JSS College of Pharmacy, Ooty, JSS Academy of Higher Education and Research, India.
Mehjabeen BanoDepartment of Pharmaceutics, JSS College of Pharmacy, Ooty, JSS Academy of Higher Education and Research, India.
Sachin Kumar SinghSchool of Pharmaceutical Sciences, Lovely Professional University, Phagwara, India.
Monica GulatiFaculty of Applied Medical Sciences, Lovely Professional University, Phagwara, India.
Veera Venkata Satyanarayana Reddy KarriDepartment of Pharmaceutics, JSS College of Pharmacy, Ooty, JSS Academy of Higher Education and Research, India.
JSS Academy of Higher Education and Research · INLovely Professional University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetic wound is a major problem that often needs amputation of the concerned organ in patients suffering from diabetes. In diabetes, the prolonged phase of inflammation obstructs the further phases of healing which, in turn, lead to improper healing of the wounds in diabetes. Pioglitazone (Pio) hydrochloride is an antidiabetic drug with reported anti-inflammatory properties. The aim of this study was to develop a Pio-nanostructured lipid carrier (Pio-NLC)-loaded collagen/chitosan (COL-CS) scaffold and evaluate its healing ability in diabetic wounds. The results of characterization of composite scaffolds reveal that cross-linked scaffolds possess optimum porosity, low matrix degradation, and sustained drug release compared with noncross-linked scaffolds. The

Indexed as

chitosancollagennanostructured lipid carrierpioglitazonescaffold and diabetic wound

Identifiers

PMID31737408
PMCPMC6855294
OpenAlexW2923112738

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.