Evidence map›Paper›PMID 31737384›Full record

ArticleCase reports in immunology2019

Evidence that a STAT3 Mutation Causing Hyper IgE Syndrome Leads to Repression of Transcriptional Activity.

Sameer Bahal, Maha E Houssen, Ania Manson, Lorena Lorenzo, Mark A Russell, Noel G Morgan, Fariba Tahami, Sofia Grigoriadou

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Case reports in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Sameer BahalDepartment of Immunology, Royal London Hospital, Barts Health NHS Trust, London, UK.ORCID https://orcid.org/0000-0002-5541-3705
Maha E HoussenUniversity of Exeter Medical School, UK.
Ania MansonDepartment of Immunology, Addenbrooke's Hospital, Cambridge, UK.
Lorena LorenzoDepartment of Immunology, Royal London Hospital, Barts Health NHS Trust, London, UK.
Mark A RussellUniversity of Exeter Medical School, UK.
Noel G MorganUniversity of Exeter Medical School, UK.
Fariba TahamiDepartment of Immunology, Great Ormond Street Hospital, London, UK.
Sofia GrigoriadouDepartment of Immunology, Royal London Hospital, Barts Health NHS Trust, London, UK.ORCID https://orcid.org/0000-0002-9863-425X
Barts Health NHS Trust · GBUniversity of Exeter · GBAddenbrooke's Hospital · GBDamanhour University · EGGreat Ormond Street Hospital · GB

Funding

Medical Research Council MR/S021930/1
6 · The paper itself

Abstract

We present the case of a 19-year-old female with a mild form of Autosomal Dominant Hyper IgE syndrome (HIES) associated with a loss-of-function mutation in

Identifiers

PMID31737384
PMCPMC6815622
OpenAlexW2980196513

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.