ArticleCase reports in hematology2019
A Rare Complication of Thymoma: Pure White Cell Aplasia in Good's Syndrome.
Article in Case reports in hematology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.
- When the Good Syndrome Goes Bad: A Systematic Literature Review.Frontiers in immunology · 2021Pooled it
- Pure White Cell Aplasia, an Exceedingly Rare Complication of a Thymoma, and Immune Reconstitution Following Bone Marrow Recovery.Hematology reports · 2025Article
- Good syndrome presenting with multiple pulmonary infections: a case report involving metagenomic sequencing diagnosis.Frontiers in medicine · 2025Article
- [Pure white cell aplasia combined with thymoma and lung cancer: a case report and literature review].Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi · 2024Review
- Pure white cell aplasia an exceptional condition in the immunological conundrum of thymomas: Responses to immunosuppression and literature review.Clinical case reports · 2022Article
- Pure White Cell Aplasia and Immune Thrombocytopenia after Thymoma Resection: A Case Report and Review of the Literature.Case reports in hematology · 2022Article
- GoodZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2021Review
- Recurrent neutropenia and chronic diarrhea following thymectomy: the good, the bad, and the ugly.Journal of community hospital internal medicine perspectives · 2021Article
- Autoimmune disorders and paraneoplastic syndromes in thymoma.Journal of thoracic disease · 2020Review
- A Large Thymoma Resected via Left Antero-lateral Thoracotomy.Cancer diagnosis & prognosisArticle
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pure white cell aplasia (PWCA) is a rare manifestation of thymoma. It is characterized by agranulocytosis with absent myeloid precursors in the bone marrow and normal hematopoiesis for other cell lines. Here we describe a 65-year-old female patient who presented with three days of fever and night sweat. Chest CT revealed an anterior mediastinal mass. A biopsy of the mass confirmed a diagnosis of thymoma mixed type A and B2. The patient developed a severe neutropenia, and her bone marrow revealed significantly decreased neutrophil-lineage cells, rare to absent B cells, and defective T cells, consistent with PWCA. Following thymectomy, a complete resolution of PWCA was achieved via multimodality therapy of intravenous immunoglobulins, granulocyte colony-stimulating factor, and immunosuppressant. This report highlights the care complexity regarding treatment choices and decision to perform thymectomy in patients presenting with PWCA.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.