ArticleInternational journal of surgical oncology2019
Thyroidectomy as Treatment of Choice for Differentiated Thyroid Cancer.
Article in International journal of surgical oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Local infiltration anesthesia (anterior field block) vs. general anesthesia for thyroidectomy: effects on operative time, complications, and cost-a GRADE-assessed systematic review and meta-analysis with subgroup analysis.Frontiers in surgery · 2026Pooled it
- The Effect of Prophylactic Protection of Inferior Parathyroid Gland Vein Blood Supply on Reducing Postoperative Hypoparathyroidism.Cancer medicine · 2026Article
- Predictors of post-operative complications following thyroid surgeries at a tertiary hospital in Tanzania.Surgery in practice and science · 2026Article
- Transaxillary vs. Transsubclavian Gasless endoscopic thyroidectomy approaches for papillary thyroid cancer.Scientific reports · 2025Article
- METTL3-mediated m6A Modification of hsa_circ_0131922 Attenuates the Progression of Papillary Thyroid Cancer by Regulating the p53 Pathway.Endocrine, metabolic & immune disorders drug targets · 2025Article
- Review
- Redo Thyroidectomy: Updated Insights.Journal of clinical medicine · 2024Review
- Preoperative ultrasound identification and localization of the inferior parathyroid glands in thyroid surgery.Frontiers in endocrinology · 2023Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDespite a large amount of data, the optimal surgical management of differentiated thyroid cancer remains controversial. Current guidelines recommend total thyroidectomy if primary thyroid cancer is >4 cm, while for tumors that are between 1 and 4 cm in size, either a bilateral or a unilateral thyroidectomy may be appropriate as surgical treatment. In general, total thyroidectomy would seem to be preferable because subtotal resection can be correlated with a higher risk of local recurrences and cervical lymph node metastases; on the other hand, total thyroidectomy is associated with more complications.
methodsThis is a retrospective study conducted on 359 patients with differentiated thyroid cancer, subjected to total thyroidectomy. Our aim was to correlate clinical and pathological features (extrathyroid tumor growth, bilaterality, nodal and distant metastasis) with patient (gender and age) and tumor (size and histotype) characteristics. Moreover, we recorded postoperative complications, including hypoparathyroidism and laryngeal nerve damage.
resultsIn our study, we found a high occurrence of pathological features indicating cancer aggressiveness (bilaterality, nodal metastases, and extrathyroid invasion). On the other hand, total thyroidectomy was associated with relatively low postsurgical complication rates.
conclusionsOur data support the view that total thyroidectomy remains the first choice for the routine treatment of differentiated thyroid cancer.
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