ArticleAmerican journal of translational research2019
LINC00994 promoted invasion and proliferation of gastric cancer cell via regulating miR-765-3p.
Article in American journal of translational research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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Who cites it
7 citing papers in PubMed, 13 citations in OpenAlex.
- LncRNA RP11-465B22.8 triggers esophageal cancer progression by targeting miR-765/KLK4 axis.Cell death discovery · 2021Article
- Interference of long non-coding RNA HAGLROS inhibits the proliferation and promotes the apoptosis of ovarian cancer cells by targeting miR-26b-5p.Experimental and therapeutic medicine · 2021Article
- CD45ROTheranostics · 2021Article
- The COX10-AS1/miR-641/E2F6 Feedback Loop Is Involved in the Progression of Glioma.Frontiers in oncology · 2021Article
- ELFN1-AS1 accelerates cell proliferation, invasion and migration via regulating miR-497-3p/CLDN4 axis in ovarian cancer.Bioengineered · 2020Article
- Clinical Value of Serum LHPP-associated miR-765 in the Prognosis of Laparoscopic or Open Hepatectomy for Hepatocellular Carcinoma.Surgical laparoscopy, endoscopy & percutaneous techniques · 2020Article
- Long Noncoding RNA LINC00173 Promotes NUTF2 Expression Through Sponging miR-765 and Facilitates Tumorigenesis in Glioma.Cancer management and research · 2020Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Emerging studies indicated that lncRNA is one crucial regulator in development and tumorigenesis. We firstly showed that LINC00994 was overexpressed in GC cells compare with GES-1. Compared to adjacent samples, the LINC00994 expression was increased in GC tissues by qRT-PCR assay. Furthermore, Elevated expression of LINC00994 induced GC cell invasion, proliferation and cycle. Luciferase reporter analysis indicated that ectopic miR-765-3p expression suppressed wild type LINC00994 luciferase activity, but not mutant LINC00994 in GC cells. Elevated expression of LINC00994 inhibited the miR-765-3p expression in GC cells. Compared to adjacent samples, the miR-765-3p expression was decreased in GC tissues by qRT-PCR assay. LINC00994 induced GC cell invasion and growth via modulating miR-765-3p. Thus, our data suggested an oncogenic role of LINC00994 in development of GC.
Indexed as
Identifiers
31737214PMC6834511W2990608468What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.