Evidence map›Paper›PMID 31737212›Full record

ArticleAmerican journal of translational research2019

MicroRNA-217/138-5p downregulation inhibits inflammatory response, oxidative stress and the induction of neuronal apoptosis in MPP

Mingda Wang, Hongming Sun, Yina Yao, Xicun Tang, Bo Wu

Abstract read
In one paragraph

Article in American journal of translational research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 33 citations in OpenAlex.

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  13. Circular RNA circ_0070441 regulates MPPMetabolic brain disease · 2022
    Article
  14. Article
  15. Article
  16. Autophagy and apoptosis cascade: which is more prominent in neuronal death?Cellular and molecular life sciences : CMLS · 2021
    Review
  17. Article
  18. Article
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  20. The antiaging property of aqueous extract ofJournal of advanced pharmaceutical technology & research
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Mingda WangSecond Department of Neurology, Daqing No. 4 Hospital Daqing 163000, China.
Hongming SunSecond Department of Neurology, Daqing No. 4 Hospital Daqing 163000, China.
Yina YaoSecond Department of Neurology, Daqing No. 4 Hospital Daqing 163000, China.
Xicun TangSecond Department of Neurology, Daqing No. 4 Hospital Daqing 163000, China.
Bo WuSecond Department of Neurology, Daqing No. 4 Hospital Daqing 163000, China.
Harbin Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parkinson's disease (PD) is a common neurodegenerative disease. Various microRNAs (miRNAs) have been reported to play important roles in cell growth regulation and inflammatory reaction. However, the detailed roles of miR-217 and miR-138-5p in PD progression remain to be investigated. In the present study, we explored the effects and underlying mechanisms of miR-217 and miR-138-5p on the inflammatory response, oxidative stress and the induction of neuronal apoptosis in an

Indexed as

microRNA-138-5pmicroRNA-217MPP+Parkinson’s diseaseSH-SY5Y cellsSIRT1

Identifiers

PMID31737212
PMCPMC6834497
OpenAlexW2995024742

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.