Evidence map›Paper›PMID 31737202›Full record

ArticleAmerican journal of translational research2019

High expression of polo-like kinase 1 is associated with TP53 inactivation, DNA repair deficiency, and worse prognosis in ER positive Her2 negative breast cancer.

Takashi Takeshita, Mariko Asaoka, Eriko Katsuta, Sara J Photiadis, Sumana Narayanan, Li Yan, Kazuaki Takabe

Open access · greenAbstract read
In one paragraph

Article in American journal of translational research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
3.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 49 citations in OpenAlex.

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  6. Immune Cytolytic Activity and Strategies for Therapeutic Treatment.International journal of molecular sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Takashi TakeshitaBreast Surgery, Department of Surgical Oncology, Roswell Park Comprehensive Cancer Center Buffalo, NY, USA.
Mariko AsaokaBreast Surgery, Department of Surgical Oncology, Roswell Park Comprehensive Cancer Center Buffalo, NY, USA.
Eriko KatsutaBreast Surgery, Department of Surgical Oncology, Roswell Park Comprehensive Cancer Center Buffalo, NY, USA.
Sara J PhotiadisDepartment of Surgery, University at Buffalo Jacobs School of Medicine and Biomedical Sciences, The State University of New York Buffalo, NY, USA.
Sumana NarayananDepartment of Surgical Oncology, Mount Sinai Medical Center Miami Beach, FL 33140, USA.
Li YanDepartment of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center Buffalo, NY, USA.
Kazuaki TakabeBreast Surgery, Department of Surgical Oncology, Roswell Park Comprehensive Cancer Center Buffalo, NY, USA.
Roswell Park Comprehensive Cancer Center · USMount Sinai Medical Center · USUniversity at Buffalo, State University of New York · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polo-like kinase 1 (

Indexed as

breast cancer subtypescell cyclehomologous recombination deficiencyPLK1TP53worse prognosis

Identifiers

PMID31737202
PMCPMC6834504
OpenAlexW2998039482

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.