Evidence map›Paper›PMID 31737078›Full record

ArticleStem cells international2019

Static Magnetic Field Induced Neural Stem/Progenitor Cell Early Differentiation and Promotes Maturation.

Shih-Yin Ho, I-Chun Chen, Yi-Jyun Chen, Chien-Hsing Lee, Chao-Ming Fu, Fei-Chih Liu, Horng-Huei Liou

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Stem cells international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Shih-Yin HoDepartment of Neurology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei 10051, Taiwan.ORCID https://orcid.org/0000-0002-5364-7428
I-Chun ChenDepartment and Graduate Institute of Pharmacology, College of Medicine, National Taiwan University, Taipei 10051, Taiwan.
Yi-Jyun ChenDepartment of Neurology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei 10051, Taiwan.
Chien-Hsing LeeDepartment and Graduate Institute of Pharmacology, College of Medicine, National Taiwan University, Taipei 10051, Taiwan.ORCID https://orcid.org/0000-0002-0576-7150
Chao-Ming FuDepartment of Physics, National Taiwan University, Taipei 10617, Taiwan.
Fei-Chih LiuDepartment of Neurology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei 10051, Taiwan.
Horng-Huei LiouDepartment of Neurology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei 10051, Taiwan.ORCID https://orcid.org/0000-0001-6537-5346
National Taiwan University · TWKaohsiung Medical University · TWNational Taiwan University Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The potential impacts of magnetic field exposures on brain development have raised public concern. In the present study, we aimed to investigate the biophysical effects of moderate-intensity (0.5 T, Tesla) static magnetic field (SMF) on mice neural progenitor cells (mNPCs). Our results showed that the SMF exposure increased the number of neurosphere formation and enhanced proliferative activity in mNPCs. In addition, our flow cytometry data demonstrated that the proportions of S phase and G2/M phase mNPCs were remarkably increased following 5 days of SMF exposure. Moreover, the level of a mitotic regulatory protein, cyclin B, was upregulated after SMF exposure. Furthermore, the mNPCs exposed to SMF exhibited a significant increase in Sox2 expression. When mNPCs were induced to differentiation, our immunofluorescence assay revealed that the percentage of neurons (Tuj-1-positive cells) but not astrocyte (s100

Identifiers

PMID31737078
PMCPMC6816009
OpenAlexW2980741953

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.