Evidence map›Paper›PMID 31736965›Full record

ArticleFrontiers in immunology2019

B Cell-Based Vaccine Transduced With ESAT6-Expressing Vaccinia Virus and Presenting α-Galactosylceramide Is a Novel Vaccine Candidate Against ESAT6-Expressing Mycobacterial Diseases.

Bo-Eun Kwon, Jae-Hee Ahn, Eun-Kyoung Park, Hyunjin Jeong, Hyo-Ji Lee, Yu-Jin Jung, Sung Jae Shin, Hye-Sook Jeong, Jung Sik Yoo, EunKyoung Shin and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Effects of non-tuberculous mycobacteria on BCG vaccine efficacy: A narrative review.Journal of clinical tuberculosis and other mycobacterial diseases · 2024
    Review
  3. Microorganisms · 2022
    Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Host Immune Response and Novel Diagnostic Approach to NTM Infections.International journal of molecular sciences · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 1 country.

Bo-Eun KwonLaboratory of Microbiology and Immunology, College of Pharmacy, Kangwon National University, Chuncheon, South Korea.
Jae-Hee AhnLaboratory of Microbiology and Immunology, College of Pharmacy, Kangwon National University, Chuncheon, South Korea.
Eun-Kyoung ParkLaboratory of Microbiology and Immunology, College of Pharmacy, Kangwon National University, Chuncheon, South Korea.
Hyunjin JeongLaboratory of Microbiology and Immunology, College of Pharmacy, Kangwon National University, Chuncheon, South Korea.
Hyo-Ji LeeDepartment of Biological Sciences, Kangwon National University, Chuncheon, South Korea.
Yu-Jin JungDepartment of Biological Sciences, Kangwon National University, Chuncheon, South Korea.
Sung Jae ShinDepartment of Microbiology, Institute for Immunology and Immunological Disease, Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine, Seoul, South Korea.
Hye-Sook JeongDivision of Vaccine Research, Center for Infectious Disease Research, Korea National Institute of Health (KNIH), Korea Centers for Disease Control and Prevention (KCDC), Cheongju, South Korea.
Jung Sik YooDivision of Vaccine Research, Center for Infectious Disease Research, Korea National Institute of Health (KNIH), Korea Centers for Disease Control and Prevention (KCDC), Cheongju, South Korea.
EunKyoung ShinDivision of Vaccine Research, Center for Infectious Disease Research, Korea National Institute of Health (KNIH), Korea Centers for Disease Control and Prevention (KCDC), Cheongju, South Korea.
Sang-Gu YeoSejong Institute of Health and Environment, Sejong, South Korea.
Sun-Young ChangLaboratory of Microbiology, College of Pharmacy and Research Institute of Pharmaceutical Science and Technology (RIPST), Ajou University, Suwon, South Korea.
Hyun-Jeong KoLaboratory of Microbiology and Immunology, College of Pharmacy, Kangwon National University, Chuncheon, South Korea.
Kangwon National University · KRAjou University · KRKorea Center for Disease Control and Prevention · KRKorea Disease Control and Prevention Agency · KRKorea National Institute of Health · KRSejong Institute · KRYonsei University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Early secretory antigenic target-6 (ESAT6) is a potent immunogenic antigen expressed in

Indexed as

Vaccinia virusAnimalsAntibodies, BacterialAntigen PresentationAntigens, BacterialBacterial ProteinsB-LymphocytesCytokinesDisease Models, AnimalGalactosylceramidesGene ExpressionImmunizationMiceT-Lymphocyte SubsetsTuberculosisTuberculosis Vaccinesalpha-galactosylceramideAntibodies, BacterialAntigens, BacterialBacterial ProteinsCytokinesESAT-6 protein, Mycobacterium tuberculosisGalactosylceramidesTuberculosis VaccinesESAT6Mycobacterium kansasiiMycobacterium tuberculosisnon-tuberculous mycobacteriavaccineα-galactosylceramide

Identifiers

PMID31736965
PMCPMC6830241
OpenAlexW2982403255

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.