Evidence map›Paper›PMID 31736945›Full record

ArticleFrontiers in immunology2019

Disparate Tuberculosis Disease Development in Macaque Species Is Associated With Innate Immunity.

Karin Dijkman, Richard A W Vervenne, Claudia C Sombroek, Charelle Boot, Sam O Hofman, Krista E van Meijgaarden, Tom H M Ottenhoff, Clemens H M Kocken, Krista G Haanstra, Michel P M Vierboom and 1 more

Open access · goldAbstract readComparative Study
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 40 citations in OpenAlex.

  1. Pooled it
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  11. Frontiers in immunology · 2025
    Article
  12. Natural outbreak ofJournal of toxicologic pathology · 2024
    Article
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  15. Article
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  17. Animal models for COVID-19 and tuberculosis.Frontiers in immunology · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Karin DijkmanTB Research Group, Department of Parasitology, Biomedical Primate Research Centre, Rijswijk, Netherlands.
Richard A W VervenneTB Research Group, Department of Parasitology, Biomedical Primate Research Centre, Rijswijk, Netherlands.
Claudia C SombroekTB Research Group, Department of Parasitology, Biomedical Primate Research Centre, Rijswijk, Netherlands.
Charelle BootTB Research Group, Department of Parasitology, Biomedical Primate Research Centre, Rijswijk, Netherlands.
Sam O HofmanTB Research Group, Department of Parasitology, Biomedical Primate Research Centre, Rijswijk, Netherlands.
Krista E van MeijgaardenDepartment of Infectious Diseases, Leiden University Medical Centre, Leiden, Netherlands.
Tom H M OttenhoffDepartment of Infectious Diseases, Leiden University Medical Centre, Leiden, Netherlands.
Clemens H M KockenTB Research Group, Department of Parasitology, Biomedical Primate Research Centre, Rijswijk, Netherlands.
Krista G HaanstraTB Research Group, Department of Parasitology, Biomedical Primate Research Centre, Rijswijk, Netherlands.
Michel P M VierboomTB Research Group, Department of Parasitology, Biomedical Primate Research Centre, Rijswijk, Netherlands.
Frank A W VerreckTB Research Group, Department of Parasitology, Biomedical Primate Research Centre, Rijswijk, Netherlands.
Biomedical Primate Research Centre · NLLeiden University Medical Center · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While tuberculosis continues to afflict mankind, the immunological mechanisms underlying TB disease development are still incompletely understood. Advanced preclinical models for TB research include both rhesus and cynomolgus macaques (

Indexed as

Mycobacterium tuberculosisAnimalsCytokinesImmunity, InnateLungMacaca fascicularisMacaca mulattaMaleTuberculosis, PulmonaryCytokinesexperimental models of diseaseinnate immunitynon-human primatespulmonary immunologytuberculosis

Identifiers

PMID31736945
PMCPMC6838139
OpenAlexW2983514447

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.