Evidence map›Paper›PMID 31736856›Full record

ArticleFrontiers in neurology2019

Amyloid Beta Oligomers Target to Extracellular and Intracellular Neuronal Synaptic Proteins in Alzheimer's Disease.

Yu Ding, Jiahui Zhao, Xunle Zhang, Shanshan Wang, Kirsten L Viola, Frances E Chow, Yang Zhang, Carol Lippa, William L Klein, Yuesong Gong

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neurology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 64 citations in OpenAlex.

  1. Article
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  11. Article
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  13. Tau and Amyloid β Protein in Patient-Derived Aqueous Brain Extracts Act Concomitantly to Disrupt Long-Term PotentiationThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  14. Article
  15. Review
  16. Article
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  18. Article
  19. Central nervous system effects of 5-HTMolecular medicine (Cambridge, Mass.) · 2022
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Yu DingJiangsu Key Laboratory for Functional Substance of Chinese Medicine, Department of Biopharmaceutics and Food Science, Nanjing University of Chinese Medicine, Nanjing, China.
Jiahui ZhaoJiangsu Key Laboratory for Functional Substance of Chinese Medicine, Department of Biopharmaceutics and Food Science, Nanjing University of Chinese Medicine, Nanjing, China.
Xunle ZhangJiangsu Key Laboratory for Functional Substance of Chinese Medicine, Department of Biopharmaceutics and Food Science, Nanjing University of Chinese Medicine, Nanjing, China.
Shanshan WangJiangsu Key Laboratory for Functional Substance of Chinese Medicine, Department of Biopharmaceutics and Food Science, Nanjing University of Chinese Medicine, Nanjing, China.
Kirsten L ViolaDepartment of Neurobiology and Neurology, Northwestern University, Evanston, IL, United States.
Frances E ChowDepartment of Neurology, Drexel University College of Medicine, Philadelphia, PA, United States.
Yang ZhangJiangsu Key Laboratory for Functional Substance of Chinese Medicine, Department of Biopharmaceutics and Food Science, Nanjing University of Chinese Medicine, Nanjing, China.
Carol LippaDepartment of Neurology, Drexel University College of Medicine, Philadelphia, PA, United States.
William L KleinDepartment of Neurobiology and Neurology, Northwestern University, Evanston, IL, United States.
Yuesong GongJiangsu Key Laboratory for Functional Substance of Chinese Medicine, Department of Biopharmaceutics and Food Science, Nanjing University of Chinese Medicine, Nanjing, China.
Nanjing University of Chinese Medicine · CNDrexel University · USNorthwestern University · US

Funding

NEUROLOGICAL DEFICITS DUE TO TOXIC A BETA OLIGOMERSR01AG018877 · NIA · NORTHWESTERN UNIVERSITY · PI KLEIN, WILLIAM L · 2001 to 2003
$890k
Pathogenic Template of Natural Oligomer of Beta-Amyloid in Alzheimer's DiseaseR21AG031388 · NIA · DREXEL UNIVERSITY · PI GONG, YUESONG · 2008 to 2009
$319k
NIA NIH HHS R01 AG018877NIA NIH HHS R21 AG031388
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Alzheimer's diseaseantibody to soluble Aβ oligomerspostsynaptic densityShank3soluble Aβ oligomerssynapsesynGapα3-Na/K-ATPase

Identifiers

PMID31736856
PMCPMC6838211
OpenAlexW2982177473

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.