Evidence map›Paper›PMID 31736815›Full record

ArticleFrontiers in psychology2019

Dose-Response Matters! - A Perspective on the Exercise Prescription in Exercise-Cognition Research.

Fabian Herold, Patrick Müller, Thomas Gronwald, Notger G Müller

Abstract read
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In one paragraph

Article in Frontiers in psychology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 112 papers, 14 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
112citing papers in PubMed, 14 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

112 citing papers in PubMed, 14 syntheses or guidelines pooled it.

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  14. The Effects of Exercise on BDNF Levels in Adolescents: A Systematic Review with Meta-Analysis.International journal of environmental research and public health · 2020
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52 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Fabian HeroldResearch Group Neuroprotection, German Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.
Patrick MüllerResearch Group Neuroprotection, German Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.
Thomas GronwaldDepartment Performance, Neuroscience, Therapy and Health, Medical School Hamburg, University of Applied Sciences and Medical University, Hamburg, Germany.
Notger G MüllerResearch Group Neuroprotection, German Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In general, it is well recognized that both acute physical exercises and regular physical training influence brain plasticity and cognitive functions positively. However, growing evidence shows that the same physical exercises induce very heterogeneous outcomes across individuals. In an attempt to better understand this interindividual heterogeneity in response to acute and regular physical exercising, most research, so far, has focused on non-modifiable factors such as sex and different genotypes, while relatively little attention has been paid to exercise prescription as a modifiable factor. With an adapted exercise prescription, dosage can be made comparable across individuals, a procedure that is necessary to better understand the dose-response relationship in exercise-cognition research. This improved understanding of dose-response relationships could help to design more efficient physical training approaches against, for instance, cognitive decline.

Indexed as

cognitionneuroplasticityneuroprotectionpersonalized medicinepersonalized trainingphysical activity

Identifiers

PMID31736815
PMCPMC6839278

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.