Evidence map›Paper›PMID 31736781›Full record

ReviewFrontiers in physiology2019

Post-activation Potentiation Versus Post-activation Performance Enhancement in Humans: Historical Perspective, Underlying Mechanisms, and Current Issues.

Anthony J Blazevich, Nicolas Babault

Registry-linked trialOpen access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07542119 (Effect of Conditioning Activities on Neuromuscular Performance in Female Invasion Sports Athletes), which is not on this map. Cited by 331 papers, 16 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
331citing papers in PubMed, 16 pooled it
16.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07542119 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Effect of Conditioning Activities on Neuromuscular Performance in Female Invasion Sports Athletes

TypeinterventionalSponsorUniversidade Federal do Triangulo MineiroRan2026 to 2026Enrolled20ConditionsPlacebo Effect, Physical Performance, Countermovement JumpArmspost-activation performance enhancement (PAPE) protocol
3 · Its place in the literature

Who cites it

331 citing papers in PubMed, 16 syntheses or guidelines pooled it, 565 citations in OpenAlex.

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271 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Anthony J BlazevichSchool of Medical and Health Science, Centre for Exercise and Sports Science Research (CESSR), Edith Cowan University, Joondalup, WA, Australia.
Nicolas BabaultFaculty of Sport Sciences, French National Institute of Health and Medical Research (INSERM), Unit 1093 Cognition, Action and Sensorimotor Plasticity, Centre for Performance Expertise, University of Burgundy and Franche-Comté, Dijon, France.
Edith Cowan University · AUInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Post-activation potentiation (PAP) is a well-described phenomenon with a short half-life (~28 s) that enhances muscle force production at submaximal levels of calcium saturation (i.e., submaximal levels of muscle activation). It has been largely explained by an increased myosin light chain phosphorylation occurring in type II muscle fibers, and its effects have been quantified in humans by measuring muscle twitch force responses to a bout of muscular activity. However, enhancements in (sometimes maximal) voluntary force production detected several minutes after high-intensity muscle contractions are also observed, which are also most prominent in muscles with a high proportion of type II fibers. This effect has been considered to reflect PAP. Nonetheless, the time course of myosin light chain phosphorylation (underpinning "classic" PAP) rarely matches that of voluntary force enhancement and, unlike PAP, changes in muscle temperature, muscle/cellular water content, and muscle activation may at least partly underpin voluntary force enhancement; this enhancement has thus recently been called post-activation performance enhancement (PAPE) to distinguish it from "classical" PAP. In fact, since PAPE is often undetectable at time points where PAP is maximal (or substantial), some researchers have questioned whether PAP contributes to PAPE under most conditions

Indexed as

methodologymusclemyosin phosphorylationneuromuscularperformancetemperaturewarm-up

Identifiers

PMID31736781
PMCPMC6838751
OpenAlexW2989082679

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.