Evidence map›Paper›PMID 31736743›Full record

ArticleFrontiers in pharmacology2019

Aberrant Scinderin Expression Correlates With Liver Metastasis and Poor Prognosis in Colorectal Cancer.

Qi Lin, Jun Li, Dexiang Zhu, Zhengchuan Niu, Xiangou Pan, Pingping Xu, Meiling Ji, Ye Wei, Jianmin Xu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Scinderin promotes glioma cell migration and invasionWorld journal of clinical oncology · 2024
    Article
  4. Article
  5. Article
  6. Gut microbes · 2023
    Article
  7. Article
  8. Article
  9. Article
  10. Targeting AVIL, a New Cytoskeleton Regulator in Glioblastoma.International journal of molecular sciences · 2021
    Review
  11. Article
  12. Article
  13. Differential expression ofEXCLI journal · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Qi LinDepartment of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Jun LiDepartment of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Dexiang ZhuDepartment of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Zhengchuan NiuDepartment of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Xiangou PanDepartment of Radiology, Zhongshan Hospital, Fudan University, Shanghai, China.
Pingping XuDepartment of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Meiling JiDepartment of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Ye WeiDepartment of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Jianmin XuDepartment of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Fudan University · CNThe First Affiliated Hospital, Sun Yat-sen University · CNSun Yat-sen University · CNZhongshan Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many genes and mutations have been reported for colorectal cancer (CRC); however, very few have been associated with colorectal cancer liver metastasis (CRLM). We performed gene expression profiling experiments to identify genetic markers for CRLM and elucidate the molecular mechanisms. Microarray experiments were performed on CRC primary tumor samples with or without liver metastasis (LM) using the Affymetrix U133 plus 2.0 GeneChip Array. A new identified gene-scinderin (

Indexed as

colorectal cancergenome-wide association studyliver metastasisprognosisscinderin

Identifiers

PMID31736743
PMCPMC6836707
OpenAlexW2983898627

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.