ArticleFrontiers in neuroscience2019
White Matter Language Pathways and Language Performance in Healthy Adults Across Ages.
Article in Frontiers in neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 35 citations in OpenAlex.
- The Association Between Changes in White Matter Microstructure and Cognitive Function in Older Adults with Mild Cognitive Impairment.Brain sciences · 2026Article
- Multimodal Graphical Network Analysis of Small-for-Gestational-Age in Preterm Infants: Integrating Neonatal Brain Volume, Structural Connectivity, and Early Neurodevelopmental Outcome.Annals of biomedical engineering · 2026Article
- Neuroimaging Correlates of the NIH Toolbox Cognition and Trail Making Tests: Normative Benchmarks in Healthy Aging.Clinical and translational neuroscience · 2026Article
- Frontal Vulnerability versus Temporal Resilience within the Core Language Network: Neuro-compensatory Mechanisms Underline Differential Language Aging Trajectories.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Fiber microstructure quantile (FMQ) regression: A novel statistical approach for analyzing white matter bundles from periphery to core.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Assessing the Utility of Predicted Brain Age for Explaining Variability in Language Abilities in Healthy Older Adults.Neurobiology of language (Cambridge, Mass.) · 2025Article
- ESTIMATING FIBER ORIENTATION DISTRIBUTION WITH APPLICATION TO STUDY BRAIN LATERALIZATION USING HCP D-MRI DATA.The annals of applied statistics · 2024Article
- A comparison of white matter microstructure and correlates with neuropsychological measures in younger and older adults.PloS one · 2024Article
- Multiple sclerosis is associated with differences in semantic memory structure.Neuropsychology · 2024Article
- Sentence completion in progressive supranuclear palsy following transcranial direct current stimulation.NPJ Parkinson's disease · 2023Article
- Properties of white matter tract diffusivity in children with developmental dyslexia and comorbid attention deficit/hyperactivity disorder.Journal of neurodevelopmental disorders · 2023Article
- White matter microstructure and receptive vocabulary in children with cerebral palsy: The role of interhemispheric connectivity.PloS one · 2023Article
- Associations between Brain Microstructure and Phonological Processing Ability in Preschool Children.Children (Basel, Switzerland) · 2022Article
- Grading scale based on arcuate fasciculus segmentation to predict postoperative language outcomes of brain arteriovenous malformations.Stroke and vascular neurology · 2022Article
- Cerebral White Matter Mediation of Age-Related Differences in Picture Naming Across Adulthood.Neurobiology of language (Cambridge, Mass.) · 2022Article
- White matter association tracts underlying language and theory of mind: An investigation of 809 brains from the Human Connectome Project.NeuroImage · 2022Article
- Differences in Diffusion Tensor Imaging White Matter Integrity Related to Verbal Fluency Between Young and Old Adults.Frontiers in aging neuroscience · 2021Article
- Differential Associations of White Matter Brain Age With Language-Related Mechanisms in Word-Finding Ability Across the Adult Lifespan.Frontiers in aging neuroscience · 2021Article
- Analysis of Age-Related White Matter Microstructures Based on Diffusion Tensor Imaging.Frontiers in aging neuroscience · 2021Article
- Effects of age and sex on clinical high-risk for psychosis in the community.World journal of psychiatry · 2020Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
The goal of this study was to determine the relationship between age-related white matter changes, with a specific focus on previously identified language pathways, and language functioning in healthy aging. 228 healthy participants (126 female; 146 right-handed), ages 18 to 76, underwent 3.0 Tesla MR diffusion weighted imaging (DWI) and a battery of language assessments including the Boston Naming Test (BNT), the Peabody Picture Vocabulary Test (PPVT), the Controlled Oral Word Association Test (COWAT), Semantic Fluency Test (SFT), and a subset of the Boston Diagnostic Aphasia Examination (CI-BDAE). Using tract based spatial statistics (TBSS), we investigated measurements of fractional anisotropy (FA), axial diffusivity (AD), radial diffusivity (RD), and mean diffusivity (MD). TBSS was used to create a white matter skeleton that was then used to analyze white matter changes (indexed by FA, AD, RD, and MD) with age and language performance. Results focused primarily on significant relationships (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.