ArticleEnvironmental microbiology2020
Subpopulations of hyphae secrete proteins or resist heat stress in Aspergillus oryzae colonies.
Article in Environmental microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed, 19 citations in OpenAlex.
- AozC, a zn(II)Microbial cell factories · 2025Article
- Fungi as Turing automata with oracles.Royal Society open science · 2024Article
- Inter- and intra-species heterogeneity in germination of Aspergillus conidia.Antonie van Leeuwenhoek · 2022Article
- A Nuclei-Based Conceptual Model of (Eco)evolutionary Dynamics in Fungal Heterokaryons.Frontiers in microbiology · 2022Article
- Membrane Traffic inJournal of fungi (Basel, Switzerland) · 2021Review
- Article
- Apical but not sub-apical hyphal compartments are self-sustaining in growth.Antonie van Leeuwenhoek · 2020Article
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hyphae at the outer part of colonies of Aspergillus niger and Aspergillus oryzae are heterogeneous with respect to transcriptional and translational activity. This heterogeneity is maintained by Woronin body mediated closure of septal pores that block interhyphal mixing of cytoplasm. Indeed, heterogeneity between hyphae is abolished in ΔhexA strains that lack Woronin bodies. The subpopulation of hyphae with high transcriptional and translational activity secretes enzymes that degrade the substrate resulting in breakdown products that serve as nutrients. The role of hyphae with low transcriptional and translational activity was not yet known. Here, we show that this subpopulation is more resistant to environmental stress in A. oryzae, in particular to temperature stress, when compared to hyphae with high transcriptional and translational activity. Notably, all hyphae of the ΔhexA strain of A. oryzae were sensitive to heat stress explained by the reduced heterogeneity in this strain. Together, we show that different subpopulations of hypha secrete proteins and resist heat stress showing the complexity of a fungal mycelium.
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