ArticleThe EMBO journal2019
Pathogen-induced pH changes regulate the growth-defense balance in plants.
Article in The EMBO journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
56 citing papers in PubMed, 119 citations in OpenAlex.
- Dynamic Assembly and Multifunctional Roles of Plant Endophytic Microbiomes.Microorganisms · 2026Review
- Biosensors reveal distinct cytosolic pH and redox dynamics across seedlings in response to danger signals and pathogen infection.Journal of experimental botany · 2026Article
- A practical guide to investigating biomolecular condensates: a comment from the plant community.Science China. Life sciences · 2026Review
- Endogenous RALF peptide function is required for powdery mildew host colonization.The New phytologist · 2026Article
- Ustilago maydis Phosphatidic Acid and Phosphatidylserine-Targeting Secreted Lipase Lip3 Is Involved in Pathogenesis.Molecular plant pathology · 2026Article
- Divergent Expression of Acidic and Alkaline Pectate Lyases inMicroorganisms · 2026Article
- Chemical Composition and Structural Traits of Leaf Biomass in Selected Asparagaceae Species.Plants (Basel, Switzerland) · 2026Article
- Plant Biotic Stress: Tools and Techniques for Crop Protection.Methods in molecular biology (Clifton, N.J.) · 2026Article
- The interplay of RALF structural and signaling functions in plant-microbe interactions.PLoS pathogens · 2025Review
- The N-terminal domain of COMPANION OF CELLULOSE SYNTHASE1 promotes microtubule array formation in Arabidopsis.Plant physiology · 2025Article
- A key residue of the extracellular gate provides quality control contributing to ABCG substrate specificity.Nature communications · 2025Article
- CarboTag: a modular approach for live and functional imaging of plant cell walls.Nature methods · 2025Article
- Purine-based infochemicals and immunometabolites: a comparative review of emerging signaling pathways in plants and animals.FEMS microbiology reviews · 2025Review
- Identification ofFrontiers in microbiology · 2025Article
- Molecular tipping points in plant cell surface HQuantitative plant biology · 2025Review
- CaARP1/CaSGT1 Module Regulates Vegetative Growth and Defense Response of Pepper Plants againstPlants (Basel, Switzerland) · 2024Article
- Disrupting cell wall integrity impacts endomembrane trafficking to promote secretion over endocytic trafficking.Journal of experimental botany · 2024Article
- Exploitation of microbial activities at low pH to enhance planetary health.FEMS microbiology reviews · 2024Article
- Assaying the Effect of Peptide Treatment on HMethods in molecular biology (Clifton, N.J.) · 2024Article
- Identification of the potato (Frontiers in plant science · 2024Article
Corrections and comments
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Authors and funding
13 authors at 4 institutions in 4 countries.
Funding
Abstract
Environmental adaptation of organisms relies on fast perception and response to external signals, which lead to developmental changes. Plant cell growth is strongly dependent on cell wall remodeling. However, little is known about cell wall-related sensing of biotic stimuli and the downstream mechanisms that coordinate growth and defense responses. We generated genetically encoded pH sensors to determine absolute pH changes across the plasma membrane in response to biotic stress. A rapid apoplastic acidification by phosphorylation-based proton pump activation in response to the fungus Fusarium oxysporum immediately reduced cellulose synthesis and cell growth and, furthermore, had a direct influence on the pathogenicity of the fungus. In addition, pH seems to influence cellulose structure. All these effects were dependent on the COMPANION OF CELLULOSE SYNTHASE proteins that are thus at the nexus of plant growth and defense. Hence, our discoveries show a remarkable connection between plant biomass production, immunity, and pH control, and advance our ability to investigate the plant growth-defense balance.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.