Evidence map›Paper›PMID 31735790›Full record

ArticleInternal medicine (Tokyo, Japan)2020

Drop Head Syndrome as a Rare Complication in Mixed Connective Tissue Disease.

Midori Akagi, Masataka Umeda, Mikiko Hashisako, Kazusato Hara, Sousuke Tsuji, Yushiro Endo, Ayuko Takatani, Toshimasa Shimizu, Shoichi Fukui, Tomohiro Koga and 9 more

Open access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 3 institutions in 1 country.

Midori AkagiDepartment of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Japan.
Masataka UmedaDepartment of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Japan.
Mikiko HashisakoDepartment of Anatomic Pathology, Graduate School of Medicine Sciences, Kyushu University, Japan.
Kazusato HaraDepartment of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Japan.
Sousuke TsujiDepartment of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Japan.
Yushiro EndoDepartment of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Japan.
Ayuko TakataniDepartment of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Japan.
Toshimasa ShimizuDepartment of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Japan.
Shoichi FukuiDepartment of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Japan.
Tomohiro KogaDepartment of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Japan.
Shin-Ya KawashiriDepartment of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Japan.
Naoki IwamotoDepartment of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Japan.
Takashi IgawaDepartment of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Japan.
Kunihiro IchinoseDepartment of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Japan.
Mami TamaiDepartment of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Japan.
Hideki NakamuraDepartment of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Japan.
Tomoki OriguchiDepartment of Physical Therapy Sciences, Graduate School of Biomedical Sciences, Nagasaki University, Japan.
Daisuke NiinoNagasaki Educational and Diagnostic Center of Pathology, Nagasaki University Hospital, Japan.
Atsushi KawakamiDepartment of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Japan.
Nagasaki University · JPNagasaki University Hospital · JPKyushu University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 54-year-old woman developed drop head syndrome (DHS), Raynaud's phenomenon and creatine kinase (CK) elevation. She did not meet the international classification criteria of dermatomyositis/polymyositis, as we observed no muscle weakness, grasping pain or electromyography abnormality in her limbs, and anti-aminoacyl tRNA synthetase (ARS) antibody was negative. Cervical magnetic resonance imaging and a muscle biopsy of the trapezius muscle revealed myositis findings as the only clinical observations in muscle. These findings, along with her anti-U1-ribonucleoprotein (RNP) antibody positivity and leukopenia, resulted in a diagnosis of mixed connective tissue disease (MCTD). Prednisolone treatment significantly improved her myositis. To our knowledge, this is the first report of DHS as the only muscle complication of MCTD.

Indexed as

Antibodies, AntinuclearCreatine KinaseFemaleGlucocorticoidsHumansMiddle AgedMixed Connective Tissue DiseaseMuscle WeaknessMyositisNeck MusclesPrednisoloneRaynaud DiseaseAntibodies, AntinuclearCreatine KinaseGlucocorticoidsPrednisolonedrop head syndromemixed connective tissue diseasemyositisneck extensor muscles

Identifiers

PMID31735790
PMCPMC7086316
OpenAlexW2986868111

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.