Evidence map›Paper›PMID 31735731›Full record

ArticleCirculation journal : official journal of the Japanese Circulation Society2019

A Statement on the Appropriate Administration of Tafamidis in Patients With Transthyretin Cardiac Amyloidosis.

Jin Endo, Motoaki Sano, Yasuhiro Izumiya, Kenichi Tsujita, Kazufumi Nakamura, Nobuhiro Tahara, Koichiro Kuwahara, Takayuki Inomata, Mitsuharu Ueda, Yoshiki Sekijima and 4 more

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In one paragraph

Article in Circulation journal : official journal of the Japanese Circulation Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 35 citations in OpenAlex.

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  20. ESC heart failure · 2022
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 8 institutions in 1 country.

Jin EndoDepartment of Cardiology, Keio University School of Medicine.
Motoaki SanoDepartment of Cardiology, Keio University School of Medicine.
Yasuhiro IzumiyaDepartment of Cardiovascular Medicine, Osaka City University Graduate School of Medicine.
Kenichi TsujitaDepartment of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University.
Kazufumi NakamuraDepartment of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences.
Nobuhiro TaharaDivision of Cardiovascular Medicine, Department of Medicine, Kurume University School of Medicine.
Koichiro KuwaharaDepartment of Cardiovascular Medicine, Shinshu University School of Medicine.
Takayuki InomataDepartment of Cardiovascular Medicine, Kitasato University Kitasato Institute Hospital.
Mitsuharu UedaDepartment of Neurology, Graduate School of Medical Sciences, Kumamoto University.
Yoshiki SekijimaDepartment of Medicine (Neurology and Rheumatology), Shinshu University School of Medicine.
Yukio AndoDepartment of Neurology, Graduate School of Medical Sciences, Kumamoto University.
Hiroyuki TsutsuiDepartment of Cardiovascular Medicine, Kyusyu University.
Mitsuaki IsobeSakakibara Heart Institute.
Keiichi FukudaDepartment of Cardiology, Keio University School of Medicine.
Keio University · JPKumamoto University · JPShinshu University · JPKitasato University · JPKurume University · JPOkayama University · JPOsaka City University · JPSakakibara Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transthyretin cardiac amyloidosis is a progressive and life-threating disease that is significantly underdiagnosed, and the actual number of patients with the disease is presently unknown. Accumulation of wild-type transthyretin-derived amyloid in the heart is a common finding in very elderly patients. Recent clinical trials demonstrated that tafamidis reduced all-cause death and the number of cardiovascular hospitalizations when compared with placebo. The Japanese Ministry of Health, Labour and Welfare approved tafamidis (Vyndaqel

Indexed as

Amyloid Neuropathies, FamilialBenzoxazolesCardiomyopathiesHumansBenzoxazolestafamidisAmyloidATTR cardiac amyloidosisJapanese Circulation SocietyJapanese Ministry of Health, Labour and Welfare (JMHLW)Tafamidis

Identifiers

PMID31735731
OpenAlexW2989391930

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.