Evidence map›Paper›PMID 31735584›Full record

ArticleEpidemics2020

Measles transmission during a large outbreak in California.

Lee Worden, Sarah F Ackley, Jennifer Zipprich, Kathleen Harriman, Wayne T A Enanoria, Rae Wannier, Travis C Porco

Abstract read
In one paragraph

Article in Epidemics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Hidden Burden of a Measles Outbreak Revealed by Genomic and Transmission Models.medRxiv : the preprint server for health sciences · 2026
    Article
  2. Article
  3. Article
  4. Underimmunisation during the 2025 Texas measles outbreak.The Lancet. Infectious diseases · 2025
    Article
  5. Article
  6. Article
  7. Unwelcome return: analyzing the recent rise of measles cases in the United States.Proceedings (Baylor University. Medical Center) · 2024
    Review
  8. Article
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lee WordenFrancis I. Proctor Foundation, University of California, San Francisco, CA, USA.
Sarah F AckleyFrancis I. Proctor Foundation, University of California, San Francisco, CA, USA; Dept. of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA.
Jennifer ZipprichCalifornia Dept. of Public Health, Immunization Branch, 850 Marina Bay Parkway, Building P, Richmond, CA, USA.
Kathleen HarrimanCalifornia Dept. of Public Health, Immunization Branch, 850 Marina Bay Parkway, Building P, Richmond, CA, USA.
Wayne T A EnanoriaDept. of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA.
Rae WannierFrancis I. Proctor Foundation, University of California, San Francisco, CA, USA; Dept. of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA.
Travis C PorcoFrancis I. Proctor Foundation, University of California, San Francisco, CA, USA.

Funding

"Modeling contact investigation and rapid response"U01GM087728 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI PORCO, TRAVIS CHRISTIAN · 2011 to 2015
$2.2M
Ebola modeling: behavior, asymptomatic infection, and contacts (2019-nCoV Admin Supplement)R01GM130900 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI PORCO, TRAVIS CHRISTIAN · 2019 to 2022
$1.6M
NIGMS NIH HHS R01 GM130900NIGMS NIH HHS U01 GM087728
6 · The paper itself

Abstract

A large measles outbreak in 2014-2015, linked to Disneyland theme parks, attracted international attention, and led to changes in California vaccine policy. We use dates of symptom onset and known epidemic links for California cases in this outbreak to estimate time-varying transmission in the outbreak, and to estimate generation membership of cases probabilistically. We find that transmission declined significantly during the course of the outbreak (p = 0.012), despite also finding that estimates of transmission rate by day or by generation can overestimate temporal decline. We additionally find that the outbreak size and duration alone are sufficient in this case to distinguish temporal decline from time-invariant transmission (p = 0.014). As use of a single large outbreak can lead to underestimates of immunity, however, we urge caution in interpretation of quantities estimated from this outbreak alone. Further research is needed to distinguish causes of temporal decline in transmission rates.

Indexed as

Disease OutbreaksModels, TheoreticalCaliforniaHumansMeaslesMeasles VaccineVaccinationMeasles VaccineImmunizationMMRSubexponential transmissionVaccinationWallinga-Teunis estimation

Identifiers

PMID31735584
PMCPMC7211428

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.