Evidence map›Paper›PMID 31735104›Full record

ArticleDrug delivery2019

Eprinomectin nanoemulgel for transdermal delivery against endoparasites and ectoparasites: preparation,

Yujuan Mao, Xiaolan Chen, Bohui Xu, Yan Shen, Zixuan Ye, Birendra Chaurasiya, Li Liu, Yi Li, Xiaoling Xing, Daquan Chen

Abstract read
In one paragraph

Article in Drug delivery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Effect of Encapsulation ofACS applied materials & interfaces · 2024
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  10. Date Palm Extract (Plants (Basel, Switzerland) · 2023
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Development ofBioMed research international · 2021
    Article
  20. Current status ofJournal of pharmaceutical analysis · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yujuan MaoJiangsu Animal Husbandry and Veterinary College, Taizhou, China.
Xiaolan ChenJiangsu Animal Husbandry and Veterinary College, Taizhou, China.
Bohui XuSchool of Pharmacy, Nantong University, Nantong, China.
Yan ShenDepartment of Pharmaceutics, School of Pharmacy, China Pharmaceutical University, Nanjing, China.
Zixuan YeDepartment of Pharmaceutics, School of Pharmacy, China Pharmaceutical University, Nanjing, China.
Birendra ChaurasiyaSchool of Pharmacy, Nantong University, Nantong, China.
Li LiuJiangsu Animal Husbandry and Veterinary College, Taizhou, China.
Yi LiSchool of Pharmacy, Yantai University, Yantai, China.
Xiaoling XingJiangsu Animal Husbandry and Veterinary College, Taizhou, China.
Daquan ChenSchool of Pharmacy, Yantai University, Yantai, China.ORCID http://orcid.org/0000-0002-6796-0204

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanoemulgels are composed of O/W nanoemulsion and hydrogels and are considered as ideal carriers for the transdermal drug delivery because these have high affinity to load hydrophobic drugs. The stable formulation of eprinomectin (EPR) is very challenging because of it is high hydrophobic nature. In this work, we have prepared EPR loaded nanoemulgel for the treatment of endo- and ectoparasites. The surface morphology of optimized formulations was characterized by scanning electron microscopy. Additionally, skin permeability and irritation tests were conducted for

Indexed as

Administration, CutaneousAnimalsDrug CarriersDrug Delivery SystemsEmulsionsGelsIvermectinMaleMiceMice, Inbred ICRNanoparticlesPermeabilityRatsRats, Sprague-DawleySkinSkin AbsorptionDrug CarriersEmulsionseprinomectinGelsIvermectinBioadhesioneprinomectinnanoemulgeltransdermal delivery systemtransdermal permeability

Identifiers

PMID31735104
PMCPMC6882498

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.