ArticleJournal of assisted reproduction and genetics2019
Pericentric inversion (Inv) 9 variant-reproductive risk factor or benign finding?
Article in Journal of assisted reproduction and genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed.
- Article
- Rates of unbalanced chromosome rearrangements associated with pericentric and paracentric inversions: Analysis of molecular chromosome results in embryo samples.Genetics in medicine open · 2026Article
- Effect of pericentric inversion of chromosome 9 on reproductive outcomes in assisted reproductive technology: a propensity score-matched cohort study.Frontiers in endocrinology · 2026Article
- Meiotic determinants of unbalanced gametogenesis in chromosomal inversion carriers.Journal of human genetics · 2026Article
- Article
- Polymorphic Rearrangements of Human Chromosome 9 and Male Infertility: New Evidence and Impact on Spermatogenesis.Biomolecules · 2023Article
- Article
- Successful Live Twin Birth through IVF/ICSI from a Couple with an Infertile Father with Pericentric Inversion of Chromosome 9 (p12q13): A Case with a High Aneuploidy Rate.Medicina (Kaunas, Lithuania) · 2022Article
- Cytogenetic Investigation of Infertile Patients in Hungary: A 10-Year Retrospective Study.Genes · 2022Article
- Risk Factors Associated with Recurrent Pregnancy Loss and Outcome of Pre-Implantation Genetic Screening of Affected Couples.International journal of fertility & sterility · 2021Article
- Chromosomal polymorphisms associated with reproductive outcomes after IVF-ET.Journal of assisted reproduction and genetics · 2020Article
- Preimplantation Genetic Testing for Couples with Balanced Chromosomal Rearrangements.Journal of reproduction & infertilityArticle
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
purposeTo report the unbalanced chromosome rearrangement rate and overall aneuploidy rate in day 5/6 embryos from a series of patients who underwent in vitro fertilization (IVF) with preimplantation genetic testing for structural rearrangements (PGT-SR) for the pericentric inversion 9 variant, inv(9)(p11q13) or inv(9)(p12q13), with concurrent 24 chromosome preimplantation genetic testing for aneuploidy (PGT-A).
methodsThis was a retrospective cohort analysis. IVF cycles and embryo biopsies were performed by referring clinics. Fifty-two trophectoderm biopsy samples from seven couples were sent to a single lab for PGT-SR for an inversion 9 variant with concurrent 24 chromosome PGT-A using single-nucleotide polymorphism (SNP) microarrays with bioinformatics.
resultsThe unbalanced rearrangement rate for this embryo cohort was 0/52 (0.0%); mean maternal age per embryo was 33.3 years (range 21-39 years). The overall euploid rate was 61.5% and aneuploidy rate was 38.5%.
conclusionsChromosome 9 pericentric inversions did not result in unbalanced structural rearrangements in day 5/6 embryo samples, supporting that this population variant is not associated with increased reproductive risks.
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