ArticleBreast (Edinburgh, Scotland)2020
Outcome of breast-conserving treatment for axillary lymph node metastasis from occult breast cancer with negative breast MRI.
Article in Breast (Edinburgh, Scotland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Best treatment options for occult breast cancer: A meta-analysis.Frontiers in oncology · 2023Pooled it
- Occult lobular breast carcinoma presenting as bilateral ovarian masses: A case report.International journal of surgery case reports · 2025Article
- Proteomic profiling reveals biological processes and biomarkers involved in the pathogenesis of occult breast cancer.BMC cancer · 2025Article
- Clinicopathological features, psychological status, and prognosis of 33 patients with occult breast cancer.World journal of psychiatry · 2024Article
- Development of a Rare Earth Nanoprobe Enables In Vivo Real-Time Detection of Sentinel Lymph Node Metastasis of Breast Cancer Using NIR-IIb Imaging.Cancer research · 2023Article
- Article
- Prognostic Models Using Machine Learning Algorithms and Treatment Outcomes of Occult Breast Cancer Patients.Journal of clinical medicine · 2023Article
- Survival analysis and nomogram for early-stage occult breast cancer with positive lymph nodes based on the SEER database.Annals of translational medicine · 2022Article
- Occult breast cancer presenting as axillary lymphadenopathy - Case Report.International journal of surgery case reports · 2022Article
- Sensitive and specific detection of breast cancer lymph node metastasis through dual-modality magnetic particle imaging and fluorescence molecular imaging: a preclinical evaluation.European journal of nuclear medicine and molecular imaging · 2022Article
- Clinicopathological characteristics and treatment outcomes of occult breast cancer: a population-based study.BMC surgery · 2022Article
- Histologic Discordance Between Primary Tumor and Nodal Metastasis in Breast Cancer: Solving a Clinical Conundrum in the Era of Genomics.The oncologist · 2021Article
- The role of ultrasound elastography and virtual touch tissue imaging in the personalized prediction of lymph node metastasis of breast cancer.Gland surgery · 2021Article
- Occult breast cancer: Where are we at?Breast (Edinburgh, Scotland) · 2020Review
- Occult Breast Carcinoma Presenting with Extensive Bone Involvement in the Absence of an Identifiable Primary Breast Lesion: A Case Report.Journal of investigative medicine high impact case reportsReview
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Authors and funding
11 authors at 7 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeWe conducted this study to investigate the prognosis and failure pattern after breast-conserving treatment (BCT) in patients with occult breast cancer (OBC) with negative breast magnetic resonance imaging (MRI) (MRI-OBC). MATERIALS AND
methodsSurvival rates and failure patterns in 66 patients who received axillary lymph node dissection (ALND) and BCT for MRI-OBC between 2001 and 2013 at seven hospitals were analyzed. OBC was defined as adenocarcinoma in the axillary lymph node (ALN) +/- supraclavicular (SCN) or internal mammary lymph node (IMN) with a negative breast MRI.
resultsFifty-four patients had only ALN metastasis (ALN only), and 12 patients had ALN metastasis along with SCN or IMN metastasis (ALN + SCN/IMN). Median follow-up was 82 months. The 5-year overall, disease-free, and breast cancer-free survival rates were 93.4%, 92.1%, and 96.8%, respectively. Nine patients experienced recurrence: breast (n = 4), regional lymph nodes (RLN, n = 1), distant metastases (DM, n = 2), breast/RLN (n = 1), and breast/RLN/DM (n = 1). Five-year disease-free survival was significantly higher in ALN only patients compared to ALN + SCN/IMN patients (96.1% vs. 75.0%; p = 0.02).
conclusionsPatients with MRI-OBC were successfully treated with BCT. There was a small risk of ipsilateral breast cancer recurrence. Failure patterns depended on the extent of initial disease.
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