ReviewSeminars in cell & developmental biology2020
Convergent extension in mammalian morphogenesis.
Review in Seminars in cell & developmental biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.
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Who cites it
39 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Dynamic changes in ocular shape during human development and its implications for retina fovea formation.BioEssays : news and reviews in molecular, cellular and developmental biology · 2024Pooled it
- Tissue flow acts as a guidance cue for immune cell polarization and directional migration.Nature cell biology · 2026Article
- Epithelial-mesenchymal Wnt crosstalk directs planar cell polarity in the developing cochlea.Nature communications · 2026Article
- Sidekick2 facilitates multiciliated cell penetration through multicellular adherens junctions.bioRxiv : the preprint server for biology · 2026Article
- Progressive correction of auditory hair cell orientation in the absence of core planar cell polarity and GPR156 signaling.Development (Cambridge, England) · 2026Article
- Differential sensitivity of midline development to mitosis during and after primitive streak extension.Developmental dynamics : an official publication of the American Association of Anatomists · 2026Article
- Epithelial-Mesenchymal Wnt Crosstalk Directs Planar Cell Polarity in the Developing Cochlea.bioRxiv : the preprint server for biology · 2026Article
- IPPK-1 and IP6 contribute to ventral nerve cord assembly in C. elegans.Developmental biology · 2025Article
- Emergence of cellular nematic order is a conserved feature of gastrulation in animal embryos.ArXiv · 2025Article
- Emergence of cellular nematic order is a conserved feature of gastrulation in animal embryos.bioRxiv : the preprint server for biology · 2025Article
- Inferring active and passive mechanical drivers of epithelial convergent extension.bioRxiv : the preprint server for biology · 2025Article
- Planar polarized force propagation integrates cell behavior with tissue shaping during convergent extension.Current biology : CB · 2025Article
- Planar cell polarity zebrafish models of congenital scoliosis reveal underlying defects in notochord morphogenesis.Development (Cambridge, England) · 2024Article
- Article
- Mesenchymal Vangl1 and Vangl2 facilitate airway elongation and widening independently of the planar cell polarity complex.Development (Cambridge, England) · 2024Article
- Collective cell dynamics and luminal fluid flow in the epididymis: A mechanobiological perspective.Andrology · 2024Review
- Vangl-dependent mesenchymal thinning shapes the distal lung during murine sacculation.Developmental cell · 2024Article
- TIAM-1 regulates polarized protrusions during dorsal intercalation in the Caenorhabditis elegans embryo through both its GEF and N-terminal domains.Journal of cell science · 2024Article
- Mechanical control of neural plate folding by apical domain alteration.Nature communications · 2023Article
- A junction-dependent mechanism drives murine mammary cell intercalation for ductal elongation.Developmental cell · 2023Article
Corrections and comments
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3 authors.
Funding
Abstract
Convergent extension is a fundamental morphogenetic process that underlies not only the generation of the elongated vertebrate body plan from the initially radially symmetrical embryo, but also the specific shape changes characteristic of many individual tissues. These tissue shape changes are the result of specific cell behaviors, coordinated in time and space, and affected by the physical properties of the tissue. While mediolateral cell intercalation is the classic cellular mechanism for producing tissue convergence and extension, other cell behaviors can also provide similar tissue-scale distortions or can modulate the effects of mediolateral cell intercalation to sculpt a specific shape. Regulation of regional tissue morphogenesis through planar polarization of the variety of underlying cell behaviors is well-recognized, but as yet is not well understood at the molecular level. Here, we review recent advances in understanding the cellular basis for convergence and extension and its regulation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.