ArticleJournal of affective disorders2020
Association of antepartum depression, generalized anxiety, and posttraumatic stress disorder with infant birth weight and gestational age at delivery.
Article in Journal of affective disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.
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Who cites it
23 citing papers in PubMed, 3 syntheses or guidelines pooled it, 56 citations in OpenAlex.
- Associations between PTSD and pregnancy outcomes: systematic review and Meta- analysis.BMC pregnancy and childbirth · 2025Pooled it
- Prevalence of Perinatal Anxiety and Related Disorders in Low- and Middle-Income Countries: A Systematic Review and Meta-Analysis.JAMA network open · 2023Pooled it
- Prenatal maternal posttraumatic stress disorder as a risk factor for adverse birth weight and gestational age outcomes: A systematic review and meta-analysis.Journal of affective disorders · 2021Pooled it
- Antenatal depression and adverse birth outcomes among pregnant women living with HIV in Dar es Salaam, Tanzania.Journal of affective disorders · 2023Trial
- Prenatal anxiety, tobacco use, and infant birth weight: a multilevel analysis of PRAMS data.Archives of women's mental health · 2026Article
- Hereditary angioedema and post traumatic stress disorder: a reciprocal relationship?Orphanet journal of rare diseases · 2026Article
- Infant emergency department visits, readmission, and mortality by maternal anxiety disorder during pregnancy occurring with and without other mental health conditions: a retrospective cohort study.BMC pregnancy and childbirth · 2025Article
- Association between history of pregnancy loss and preterm birth: the mediating role of maternal anxiety.BMC pregnancy and childbirth · 2025Article
- Associations Between Mothers' COVID-Related Perceived Stress and Children's Internalizing and Externalizing Symptoms in Peru.Child psychiatry and human development · 2025Article
- Suicidal ideation and attempts among adults in eastern Ethiopia: A community-based cross-sectional study.Global mental health (Cambridge, England) · 2025Article
- Prenatal Maternal Psychological Stress (PMPS) and Its Effect on the Maternal and Neonatal Outcome: A Retrospective Cohort Study.Healthcare (Basel, Switzerland) · 2024Article
- The association between pre-pregnancy and first-trimester hair cortisol and preterm birth: a causal inference model.European journal of epidemiology · 2024Article
- Trauma and Posttraumatic Stress Disorder as Important Risk Factors for Gestational Metabolic Dysfunction.American journal of perinatology · 2024Review
- Prevalence of perinatal post-traumatic stress disorder (PTSD) in low-income and middle-income countries: a systematic review and meta-analysis.BMJ public health · 2024Article
- Maternal Wellbeing Five Years after a Very Preterm Delivery: Prevalence and Influencing Factors in a European Cohort.Children (Basel, Switzerland) · 2023Article
- Review
- Association between maternal depression and neonatal outcomes: Evidence from a survey of nationally representative longitudinal studies.Frontiers in public health · 2022Article
- Effects of Yoga exercise on anxiety and fetus growth in pregnant women with small for gestational age fetus.American journal of translational research · 2022Article
- Article
- Anxiety and depressive symptoms in pregnancy predict low birth weight differentially in male and female infants-findings from an urban pregnancy cohort in India.Social psychiatry and psychiatric epidemiology · 2021Article
Corrections and comments
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Authors and funding
8 authors at 6 institutions in 2 countries.
Funding
Abstract
backgroundLow- and middle-income countries bear a disproportionate burden of preterm birth (PTB) and low infant birth weight (LBW) complications where affective and anxiety disorders are more common in the antepartum period than in industrialized countries.
objectiveTo evaluate the extent to which early pregnancy antepartum depression, generalized anxiety disorder, and posttraumatic stress disorder (PTSD) are associated with infant birth weight and gestational age at delivery among a cohort of pregnant women in Peru.
methodsOur prospective cohort study consisted of 4408 pregnant women. Antepartum depression, generalized anxiety, and PTSD were assessed in early pregnancy using the Patient Health Questionnaire-9, Generalized Anxiety Disorder Scale-7 and PTSD Checklist - Civilian Version, respectively. Pregnancy outcome data were obtained from medical records. Multivariable linear and logistic regression procedures were used to estimate adjusted measures of association (β coefficients and odds ratios) and 95% confidence intervals (CI).
resultsAfter adjusting for confounders, women with antepartum generalized anxiety (32.6% prevalence) had higher odds of LBW (adjusted odds ratio (OR)=1.47; 95%CI: 1.10-1.95) and were more likely to deliver small for gestational age (OR = 1.39; 95%CI: 1.01-1.92) infants compared to those without anxiety. Compared to those without PTSD, women with PTSD (34.5%) had higher odds of delivering preterm (OR = 1.28; 95%CI: 1.00-1.65) yet PTSD was not associated with LBW nor gestational age at delivery. Women with antepartum depression (26.2%) were at no increased risk of delivering a preterm, low-birth-weight or small-for-gestational-age infant. LIMITATIONS: Our ability to make casual inferences from this observational study is limited; however, these findings are consistent with prior studies.
conclusionGeneralized anxiety disorder during pregnancy appeared to increase odds of delivering a low-birth-weight or small-for-gestational-age infant, while PTSD was associated with increased odds of delivering preterm. Our findings, and those of others, suggest antenatal care should be tailored to screen for and provide additional mental health services to patients.
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